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Update on prolonged and persistent diarrhea in children

机译：儿童长期和持续腹泻的最新情况

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Purpose of review To highlight recent advances in our understanding of prolonged episodes of acute diarrhea and persistent diarrhea in children. The focus is on the contribution of these illnesses to the global burden of diarrhea, their impact on childhood growth and development, novel epidemiologic links between prolonged and persistent diarrheal episodes, and strategies for their prevention and management. Recent findings Although less common than acute diarrhea, prolonged and persistent episodes of diarrhea in childhood constitute a significant portion of the global burden of diarrhea. These episodes also play a key role in the vicious cycle of childhood diarrhea and malnutrition in which undernutrition is both a risk factor and an outcome of diarrhea. Increased efforts to provide WHO-recommended zinc therapy for all children with diarrhea in developing countries will significantly reduce morbidity and mortality. In children who develop persistent diarrhea, yogurt-based or amino acid-based diets may accelerate their recovery. Summary In addition to increased implementation of strategies already known to effectively prevent and manage acute diarrhea, further research is needed to address the recognition, prevention, and treatment of prolonged episodes of acute diarrhea and persistent diarrhea in resource-limited settings.
机译：复习的目的强调我们对儿童急性腹泻和持续性腹泻的长期发作的了解方面的最新进展。重点是这些疾病对腹泻的总体负担，对儿童生长和发育的影响，长期和持续性腹泻发作之间的新型流行病学联系以及预防和管理的策略。最新发现尽管比急性腹泻少见，但儿童期长时间持续的腹泻却构成了全球腹泻负担的重要部分。这些发作在儿童腹泻和营养不良的恶性循环中也起着关键作用，其中营养不良既是危险因素，也是腹泻的结果。为发展中国家的所有腹泻儿童提供更多的世卫组织推荐的锌疗法的努力将大大降低发病率和死亡率。在持续腹泻的儿童中，以酸奶或氨基酸为主的饮食可能会加速其康复。总结除了增加已知有效预防和管理急性腹泻的策略的实施以外，还需要进一步的研究来解决在资源有限的环境中急性腹泻和持续性腹泻的长期发作的认识，预防和治疗。

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