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Blood donor iron status: Are we bleeding them dry?

机译:献血者铁的状态:我们正在干出血吗?

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PURPOSE OF REVIEW: This review examines the recent research on the prevalence, determinants and importance of low iron in blood donors, and on the efforts to reduce or prevent iron depletion in donor populations. RECENT FINDINGS: Female donors, especially younger women, are at highest risk for donation-induced low iron, but menopausal women and high-frequency donors of both sexes also face considerable risk for iron depletion. Predonation screening for hemoglobin contributes little information on donor iron status. Consumption of supplemental iron is helpful in preventing or reversing low iron, and waiting longer between donations also facilitates the recovery of the iron lost through donation. SUMMARY: Although the impact of phlebotomy-related iron depletion on donor health requires better documentation, measures are available now that can be deployed on a targeted or standardized basis. Blood centers, regulators, and donors should continue to evaluate different approaches for addressing this problem, with the likely outcome that no single measure is optimal for maintaining adequate collections while safeguarding donor health.
机译:审查的目的:这项审查审查了最近的研究,在献血者中低铁的流行,决定因素和重要性,以及为减少或防止献血者铁消耗的努力。最新发现:女性捐赠者,特别是年轻女性,因捐赠引起的低铁风险最高,但更年期的女性和男女高频捐赠者也面临铁耗竭的巨大风险。捐血前筛查血红蛋白对供体铁状态的贡献很小。补充铁的消耗有助于预防或逆转低铁,并且在捐赠之间等待更长的时间也有助于恢复因捐赠而损失的铁。简介:尽管放血相关的铁耗竭对供体健康的影响需要更好的文件记录,但是现在可以采取措施,可以有针对性地或标准化地进行部署。血液中心,监管机构和捐献者应继续评估解决该问题的不同方法,其结果可能是,没有一种单一的措施可以最佳地维持充足的采血量,同时又能保护捐献者的健康。

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