...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of physical chemistry, B. Condensed matter, materials, surfaces, interfaces & biophysical >Quantifying the Diffusion of Lipids in the Proximal/Distal Leaflets of a Supported Lipid Bilayer by Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy
【24h】

Quantifying the Diffusion of Lipids in the Proximal/Distal Leaflets of a Supported Lipid Bilayer by Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy

机译：通过二维荧光寿命相关光谱法量化支撑脂质双层近端/远端小叶中脂质的扩散

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A supported lipid bilayer (SLB) is a versatile platform for examining the dynamical properties of biomembranes. However, the effect of a prerequisite solid substrate on the dynamics of a SLB remains very elusive. Especially, it is not clarified how the diffusivity of each leaflet in a SLB is affected by the SLB solid substrate interaction. In this study, we applied two-dimensional fluorescence lifetime correlation spectroscopy to a SLB for elucidating the diffusion of lipids in the proximal and distal leaflets of a SLB. We find that the autocorrelation curve of a fluorescent lipid in the proximal leaflet decays more slowly than that in the distal leaflet, meaning that the proximal leaflet is less diffusive. This result indicates stronger interaction between the proximal leaflet and a solid substrate.
机译：支持的脂质双层（SLB）是用于检查生物膜的动态性质的通用平台。 然而，先决条件固体基质对SLB动态的影响仍然非常难以捉摸。 特别地，阐明了SLB中每个鳄的扩散性如何受到SLB固体基底相互作用的影响。 在该研究中，我们将二维荧光寿命相关光谱施加到SLB中，以阐明脂质在SLB的近端和远端小叶中的扩散。 我们发现近侧叶片中荧光脂质的自相关曲线比远端宣传片中的慢慢衰减更慢，这意味着近侧传单不太扩散。 该结果表明近端叶片和固体基材之间的相互作用更强。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号