Possible mechanisms underlying the cholesterol-raising effect of the coffee diterpene cafestol.

de Roos-B; Katan MB

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Possible mechanisms underlying the cholesterol-raising effect of the coffee diterpene cafestol.

机译：咖啡二萜cafestol的胆固醇升高作用的潜在机制。

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Cafestol, a coffee diterpene present in unfiltered coffee brews, potently raises serum lipids in humans. The mechanism through which this dietary compound influences liporotein metabolism is largely unknown. Unravelling the mechanism of action might lead to new insights into the regulation of serum cholesterol levels in humans. This review summaries ways in which cafestol may act on serum lipids.

机译：Cafestol是存在于未经过滤的咖啡冲泡物中的一种咖啡二萜，可有效提高人体的血脂。这种饮食化合物影响脂蛋白的代谢的机制尚不清楚。阐明作用机理可能导致对人类血清胆固醇水平调节的新见解。这篇综述总结了咖啡甾醇可能作用于血清脂质的方式。

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《Current opinion in lipidology》 |1999年第1期|共5页
作者
de Roos-B; Katan MB;
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正文语种 eng
中图分类生物化学;
关键词
Cholesterol; Coffee; Diterpenes; cholesterol ester transfer proteins; peroxisome proliferator activated receptor; 胆固醇; 咖啡; 二萜类;

机译：Cholesterol;Coffee;Diterpenes;cholesterol ester transfer proteins;peroxisome proliferator activated receptor;胆固醇;咖啡;二萜类;

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专利

1. Possible mechanisms underlying the cholesterol-raising effect of the coffee diterpene cafestol. [J] . de Roos-B, Katan MB Current opinion in lipidology . 1999,第1期

机译：咖啡二萜cafestol的胆固醇升高作用的潜在机制。
2. Validity of animal models for the cholesterol-raising effects of coffee diterpenes in human subjects [J] . Baukje de Roos, Janet K. Sawyer, Lawrence L. Rudel, Proceedings of the Nutrition Society . 2007,第3期

机译：动物模型对咖啡二萜类化合物对人的胆固醇升高作用的有效性
3. Mechanisms underlying the cardiovascular effects of a labdenic diterpene isolated from Moldenhawera nutans in normotensive rats. [J] . Lahlou S, de-Barros-Correia-CA Jr, Vasconcelos-Dos-Santos M, Vascular pharmacology . 2007,第1期

机译：降血压大鼠中分离自二倍体霉菌的唇形二萜的心血管作用的潜在机制。
4. METABOLITES FROM CAFESTOL - A COFFEE DITERPENE- BY ZEBRAFISH TANK MODEL AND LCMS/MS [C] . Claudia M. Rezende, Cyrus V. Andriolo, Henrique M. G. Pereira, International Mass Spectrometry Conference . 2018

机译：来自Cafestol的代谢物 - 咖啡含咖啡罐模型和LCMS / MS
5. Catalytic and regulatory mechanisms of diterpene synthesis in plants and bacteria. [D] . Mann, Francis Michelle. 2010

机译：植物和细菌中二萜合成的催化和调节机制。
6. Cholesterol-raising diterpenes in types of coffee commonly consumed in Singapore Indonesia and India and associations with blood lipids: A survey and cross sectional study [O] . Nasheen Naidoo, Cynthia Chen, Salome A Rebello, 2011

机译：在新加坡印度尼西亚和印度常用的咖啡中与胆固醇有关的二萜和与血脂的关系：一项调查和横断面研究
7. Cholesterol-raising diterpenes in types of coffee commonly consumed in Singapore, Indonesia and India and associations with blood lipids: A survey and cross sectional study [O] . Naidoo N., Chen C., Rebello S.A., 2011

机译：在新加坡，印度尼西亚和印度常用的咖啡中与胆固醇有关的二萜和与血脂的关系：一项调查和横断面研究

Possible mechanisms underlying the cholesterol-raising effect of the coffee diterpene cafestol.

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