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Fluid administration during abdominal surgery influences on coagulation in the postoperative period.

机译:腹部手术期间输液会影响术后的凝血。

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OBJECTIVE: Postoperative coagulopathy is an important concern for patients after major surgery. Our objective was to define the factors that correlate with postoperative deterioration in coagulation. DESIGN: Retrospective clinical case study. SETTING: University hospital. PARTICIPANTS: Adult patients (n = 150), who underwent major abdominal surgery, were randomly chosen to participate in the study. For each patient, demographic and medical data, anesthetic information, type and duration of surgery, hemodynamic variables, fluid administration, as well as preoperative and postoperative prothrombin time and partial thromboplastin time were collected. Statistical analysis was used to determine which factors correlated with deterioration of coagulation tests. RESULTS: We found statistically significant correlation between deteriorating coagulation functions and administration of more than 3 l of crystalloids during abdominal surgery. There was also correlation between administration of more than 500 ml of colloid administration and elongation of protrombin time. The remainder of the above studied factors did not correlate with deteriorating coagulation. CONCLUSIONS: Administration of more than 3-l cristalloids or 500-ml colloids during abdominal surgery correlates with postoperative coagulopathy.
机译:目的:术后凝血病是大手术后患者的重要关注点。我们的目标是确定与术后凝血功能恶化相关的因素。设计:回顾性临床案例研究。地点:大学医院。参与者:接受大腹部手术的成年患者(n = 150)被随机选择参加研究。对于每位患者,收集了人口统计和医学数据,麻醉信息,手术的类型和持续时间,血液动力学变量,输液量以及术前和术后凝血酶原时间和部分凝血活酶时间。使用统计分析来确定哪些因素与凝血测试的恶化相关。结果:我们发现腹部手术期间凝血功能恶化与服用3升以上的晶体之间存在统计学上的显着相关性。超过500毫升的胶体给药与延长的蛋白原时间之间也存在相关性。上述研究因素的其余部分与恶化的凝血不相关。结论:腹部手术中施用超过3-l的晶体或500 ml的胶体与术后凝血病有关。

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