...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Current opinion in anaesthesiology >Effects of red blood cell storage in heavily transfused patients
【24h】

Effects of red blood cell storage in heavily transfused patients

机译：大量输血患者红细胞储存的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose of Review: Most publications on Red Blood Cell (RBC) storage time are performed in patient groups receiving on average 1-4 RBC transfusions. Here we look at the observational results in the more heavily transfused patient populations studied, which are mostly in trauma or cardiac surgery patients. Recent Findings: New heavily transfused patient groups in which the possible detrimental effects of prolonged RBC storage were studied are HSCT and liver transplant patients. In these studies no associations of prolonged RBC storage with outcome were seen. Apart from these studies, new studies were also reported on ICU patients and cardiac surgery patients. These latter studies reported associations with infections, postoperative length of stay, and renal complications. In these studies similar shortcomings in study design and analysis were encountered as in earlier studies, leading to overestimation of the studied association. Some of the recent studies suggest, contrary to the most encountered opinion, that fresh RBC might be detrimental on some outcomes. Similar observations have recently been presented in other, less heavily transfused populations. Summary: Clinical effects of RBC storage turn out to be determined by far more aspects than storage time alone. ? 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins.
机译：审查目的：关于红细胞（RBC）储存时间的大多数出版物都是在平均接受1-4次RBC输血的患者组中进行的。在这里，我们看一下在研究的输血量更大的患者人群中的观察结果，这些人群主要在创伤或心脏外科手术患者中。最新发现：HSCT和肝移植患者是新的大量输血患者，研究了延长RBC储存的可能有害作用。在这些研究中，未发现延长的RBC储存与预后相关。除了这些研究，还报道了有关ICU患者和心脏外科手术患者的新研究。后来的这些研究报道了与感染，术后住院时间和肾脏并发症的关系。在这些研究中，与早期研究一样，在研究设计和分析中也遇到了类似的缺陷，导致对研究关联的估计过高。与大多数人的看法相反，最近的一些研究表明，新鲜的红细胞可能对某些结局有害。最近在其他较少输血的人群中也出现了类似的观察结果。摘要：事实证明，RBC储存的临床效果远比单独储存时间要多。 ？ 2013威科集团健康|利平科特·威廉姆斯和威尔金斯。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号