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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Aspiration in the otherwise healthy Infant—Is there a natural course for improvement?
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Aspiration in the otherwise healthy Infant—Is there a natural course for improvement?

机译：在其他健康婴儿的愿望 - 是有自然的改进课程吗？

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Objectives/Hypothesis Timing and indication for surgical intervention is a major challenge in managing pediatric oropharyngeal dysphagia. No study has evaluated a natural course of swallowing dysfunction in otherwise healthy infants. Our objective was to review the outcomes and time to resolution of abnormal swallow in infants with aspiration. Study Design Retrospective case series at a tertiary children's hospital. Methods Fifty patients under 1?year old with aspiration on a modified barium swallow study were included. Patients born 34?weeks, with medical or genetic comorbidities, or who underwent surgical intervention for aspiration were excluded. Patients were followed until aspiration resolved on a swallow study. Kaplan‐Meier survival analysis was performed. Results Forty patients (25 patients [50%] by 6?months, 10 [20%] by 1?year, three [6%] by 2?years, and two [4%] at the end of the follow‐up interval) were recommended a normal diet, and 10 patients (20%) were still aspirating by the end of the follow‐up interval. Median time to resolution was 202?±?7?days (range, 19–842?days), probability 48% (95% confidence interval [CI]: 0.34‐0.62). The probability of resolution at 6?months was 46% (95% CI: 0.4‐0.68), at 1?year was 64% (95% CI: 0.51‐0.77), at 2?years was 76% (95% CI: 0.64‐0.88), and at the end of the follow‐up interval 81.3% (95% CI: 0.7‐0.92). Conclusions The majority of infants with aspiration and without any other major comorbidities improved within 1?year. Future research should be directed toward better understanding swallowing dysfunction in neurologically normal infants. Level of Evidence 4 Laryngoscope , 130:514–520, 2020
机译：目的/假设时序和手术干预的迹象是管理儿科口咽吞咽困难的主要挑战。没有研究评估了诸如健康婴儿的吞咽功能障碍的自然过程。我们的目标是审查具有愿望婴儿异常吞咽的结果和时间。学习在第三节儿童医院的追溯案例系列。方法有五十名患者1岁以下的患者，患有改进的钡燕酸研究。患者出生＆ 34个星期，用医疗或遗传合并症，或者被排除在外，或接受手术干预的吸入。患有患者，直至愿望在吞咽研究中得到解决。考生梅尔存活分析进行了。结果45例患者（25名患者[50％]，6？几个月，10 [20％]达1？一年，三[6％]达2？年，两[4％]在后续间隔结束时）建议使用正常饮食，10名患者（20％）在随访间隔结束时仍在吸引。中位数到分辨率的时间是202？±7？天（范围，19-842天），概率48％（95％置信区间[CI]：0.34-0.62）。 ？分辨率的在6个月的概率为46％（95％CI：0.4-0.68），1年为64％（95％CI：0.51-0.77）？，2年为76％（95％CI： 0.64-0.88），后续间隔的结束81.3％（95％CI：0.7-0.92）。结论大多数患有愿望和没有任何其他主要的合并症的婴儿在1年内改善。未来的研究应该朝着更好地了解神经学正常婴儿的吞咽功能障碍。证据水平4喉镜，130：514-520,2020

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