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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Variability in pathologic interpretation of mandibular invasion
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Variability in pathologic interpretation of mandibular invasion

机译：下颌侵袭病理解释的可变性

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Objectives/Hypothesis Our objective was to identify the accuracy, sensitivity, and specificity of pathological interpretation of mandibular invasion by oral cavity squamous cell carcinoma (SCC) and compare the sensitivity of detecting mandibular invasion in the erosive versus the infiltrative patterns of invasion. We also aimed to describe the significance of the terminology the carcinoma “abuts the mandible” in pathologic interpretation of mandibular invasion. Study Design Retrospective case series. Methods Mandibulectomy specimens from patients who underwent surgical treatment for oral cavity SCC between January 1, 2005 and December 31, 2015 were retrospectively reviewed by a board‐certified anatomic pathologist. The accuracy of pathologic interpretation of mandibular invasion was calculated using the retrospective interpretation of bone invasion as the true interpretation, which was compared to the interpretation on the original pathology report. Incidence of encountering the terminology the carcinoma “abuts the mandible” in the pathology report was calculated. Results A series of 108 consecutive mandibulectomy specimens were reviewed. Sixty‐nine percent (74/108) of cases were interpreted as having mandibular invasion. The accuracy of interpreting mandibular invasion was 84%. The sensitivities for interpretation of mandibular invasion for the erosive and infiltrative patterns of invasion were 77% (30/39) and 91% (32/35), respectively ( P = .08). Nine percent (10/108) of pathology reports utilized the terminology the carcinoma “abuts the mandible,” and 80% (8/10) of these cases exhibited mandibular invasion. Conclusions The accuracy of identifying mandibular invasion is 84%, indicating a certain degree of sampling error and variability in interpretation. A precise pathologic definition of mandibular invasion should be applied during the interpretation of these specimens to minimize variability. Level of Evidence 4 Laryngoscope , 130:1721–1724, 2020
机译：目标/假说我们的目标是通过口腔鳞状细胞癌（SCC）来识别的准确度，灵敏度，和下颌浸润病理解释的特异性和比较的在侵蚀与入侵的浸润性图案检测入侵下颌的灵敏度。我们的目的是描述的术语癌“紧靠下颌骨”下颌骨侵袭的病理解释的意义。研究设计回顾性案例系列。方法Mandibulectomy从2005年谁1月1日和12月31日之间接受了手术治疗口腔鳞状细胞癌患者标本，2015年进行回顾性由委员会认证的解剖病理学家。下颌入侵的病理解释的准确性，使用骨侵袭的回顾性解释为真正的解释，这是相比于原来的病理报告的解释来计算。遇到的术语癌发病率“抵靠下颌骨”中的病理报告计算。结果一系列的连续108个标本mandibulectomy进行了审查。案件百分之六十九（108分之74）被解释为具有下颌入侵。解释下颌入侵的准确率为84％。用于侵入的侵蚀和浸润图案下颌入侵的解释的灵敏度分别为77％（30/39）和91％（32/35），（P = 0.08）。的所使用的术语中的癌病理报告百分之九（108分之10）“抵靠下颌骨，”和这些病例的80％（8/10）显示出下颌入侵。结论识别入侵下颌的精确度为84％，表明有一定程度的解释抽样误差和变异性。下颌入侵的精确病理定义应这些标本的解释过程中应用，以尽量减少可变性。证据4喉镜的水平，130：1721年至1724年2020年

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