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首页> 外文期刊>The Journal of Experimental Biology >Intestinal digestive enzyme modulation in house sparrow nestlings occurs within 24 h of a change in diet composition
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Intestinal digestive enzyme modulation in house sparrow nestlings occurs within 24 h of a change in diet composition

机译:House Sparrow巢穴中的肠消化酶调制发生在饮食成分变化的24小时内

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Nestling house sparrows near fledging age (12 days) were previously found to reversibly modulate the activity of their intestinal digestive enzymes in response to changes in diet composition. However, it is not known how quickly nestlings can adjust to new diets with different substrate compositions, nor is it known how early in life nestlings can modulate their enzyme activity in response to changes in diet. In the present study, 3-day-old nestlings were captured from the wild and fed and switched among contrasting diets - one high in protein and low in carbohydrate and another higher in carbohydrate and with lower, but adequate, protein - in order to determine (1) how quickly house sparrow nestlings could adjust to changes in diet composition, (2) how early in life nestlings could modulate their digestive enzyme activity in response to these changes and (3) which digestive enzymes could be modulated in house sparrow nestlings earlier in life. We found that house sparrow nestlings as young as 3 days post-hatch were capable of modulating their intestinal disaccharidase activity within 24 h of a change in diet composition, and nestlings gained the ability to modulate aminopeptidase-N by 6 or 7 days of age. To our knowledge, this is the first evidence of digestive enzyme modulation completed within 24 h of a change in diet in an avian species and the first study to show intestinal digestive enzyme modulation in response to changes in diet composition in any animal this early in development.
机译:先前,刚刚发现剩余的年龄(12天)附近的雏鸟雀斑以响应于饮食组合物的变化来反转调节其肠系消化酶的活性。然而,尚不清楚雏鸟可以如何适应具有不同底物组合物的新饮食,也不知道生活中的早期雏鸟可以在响应饮食的变化时调节其酶活性。在本研究中,从野外捕获3日历史的雏鸟,并喂养并在对比饮食中切换 - 蛋白质高,碳水化合物中的一个高,碳水化合物的另一个高,较低,但足够,蛋白质 - 为了确定(1)House Sparrow雏鸟的速度如何适应饮食成分的变化,(2)寿命雏鸟的早期可以如何调节它们的消化酶活性,以响应这些变化和(3)哪些消化酶可以在House Sparrow雏鸟中调制在生活中。我们发现,孵化后3天的房子麻雀雏鸟能够在饮食成分的变化发生24小时内调节其肠多种酶活性,并且雏鸟能够在6或7天内调节氨基肽酶-N的能力。据我们所知,这是在禽类种类的饮食变化的24小时内完成消化酶调制的第一个证据,以及第一次研究,以响应于任何动物的饮食组合物的变化而显示肠道消化酶调制。

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