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Cervicitis: a review.(Miscellaneous)

机译:宫颈炎:评论。(其他)

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Purpose of review: Sexually transmitted infections impact significantly on global health. Whereas Chlamydia, Neisseria gonorrhoea and syphilis have been extensively examined, there remains a paucity of knowledge of nonchlamydial and nongonococcal cervicitis, an arguably more prevalent but poorly characterized condition with uncertain clinical implications. With increasing application of molecular diagnostic methods for the detection of sexually transmitted infections and a growing body of literature on cervicitis, a review is timely. Recent findings: The number of putative aetiological agents implicated in cervicitis is growing and includes Mycoplasma genitalium, herpes simplex virus, cytomegalovirus, bacterial vaginosis and Trichomonas. The potential role of cervicitis in HIV transmission has been highlighted. Increasing broad-spectrum antibiotic usage with associated emergence of antimicrobial resistance reinforces the need for targeted antibiotic therapies, including the management of cervicitis. Summary: As our understanding of the aetiology and significance of cervicitis, particularly nonspecific cervicitis, improves, management will be refined. Advances in molecular diagnostic testing will facilitate this process, but urinary nucleic acid amplification testing should not replace clinical examination while cervicitis prevalence and significance is not yet established. A standardized approach to cervicitis research, particularly with consensus of case definition, may facilitate outcomes that can be more generally applied in clinical practice.
机译:审查目的:性传播感染严重影响全球健康。尽管已经广泛检查了衣原体,淋病奈瑟氏球菌和梅毒,但是对于衣原体和非淋球菌性宫颈炎的知识仍然很少,这可能是一种更为普遍但特征不明确的疾病,具有不确定的临床意义。随着分子诊断方法在检测性传播感染中的应用越来越广泛,有关宫颈炎的文献也越来越多,对此进行了及时的审查。最近的发现:与宫颈炎有关的推定病原体的数量正在增加,包括生殖器支原体,单纯疱疹病毒,巨细胞病毒,细菌性阴道病和滴虫。宫颈炎在HIV传播中的潜在作用已得到强调。广谱抗生素的使用以及相关的耐药性的出现,增加了对靶向抗生素治疗的需求,包括宫颈炎的治疗。简介:随着我们对宫颈炎(尤其是非特异性宫颈炎)的病因学和意义的认识不断提高,我们将改善治疗方法。分子诊断测试的进展将促进这一过程,但是在子宫颈炎的流行和意义尚未确定的情况下,尿核酸扩增测试不应取代临床检查。宫颈炎研究的标准化方法,尤其是在病例定义达成共识的情况下,可能会促进可在临床实践中更普遍应用的结果。

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