...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Current opinion in lipidology >Management of homozygous familial hypercholesterolaemia
【24h】

Management of homozygous familial hypercholesterolaemia

机译：纯合子家族性高胆固醇血症的治疗

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In recent years, the time trade-off (TTO) method, most commonly with a 10-year time horizon, has been the most frequently used approach for direct health state utility assessment, likely due to National Institute for Health and Care Excellence (NICE) preference for comparability with the EQ-5D, which has a utility scoring algorithm derived via this method. Although comparability to previous utility studies is important, there are situations when the TTO method may not be appropriate. The purpose of the current review is to highlight challenges to the TTO method. Five challenges to the TTO method are discussed: mild health states, small differences among health states, temporary health states, pediatric health states, and assessment of samples with particular characteristics. Some of these challenges are associated with the 10-year time horizon, while other situations may raise issues for TTO methods regardless of the time horizon. Alternative approaches for valuing health states are suggested.
机译：近年来，时间权衡（TTO）方法（通常具有10年的时间跨度）已成为直接进行健康状态效用评估的最常用方法，这可能是由于美国国立卫生研究院（NICE） ）优先考虑与EQ-5D的可比性，EQ-5D具有通过此方法得出的效用评分算法。尽管与以前的效用研究的可比性很重要，但在某些情况下，TTO方法可能不合适。本次审查的目的是强调TTO方法面临的挑战。讨论了TTO方法的五个挑战：轻度健康状态，健康状态之间的细微差异，临时健康状态，儿科健康状态以及具有特定特征的样品评估。其中一些挑战与10年时间跨度有关，而其他情况则可能与TTO方法无关，无论时间跨度如何。建议了评估健康状况的替代方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号