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Standard chemotherapy for malignant bony tumors in children and young adults

机译:儿童和青年人恶性骨肿瘤的标准化疗

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This article focuses on the evolution and rationale for chemotherapy for children and young adults with primary bone tumors; OS, ES, and PBL. Currently, there are no standard therapies for metastatic OS or ES and clinicians must either use the standard localized approaches or enroll in several new clinical trials for high-risk disease. CS, the third most common malignant bone tumor in patients younger than 50 years is a surgically managed disease and is not routinely treated with chemotherapy. As previously emphasized, participation in a clinical research trial, therapeutic, biological, registry, or cancer control, is considered the goal for all patients and is in fact, the "standard of care" for children with cancer.
机译:本文重点探讨患有原发性骨肿瘤的儿童和青少年的化学疗法的发展和原理。 OS,ES和PBL。当前,尚无用于转移性OS或ES的标准疗法,临床医生必须使用标准的局部方法或参加一些针对高危疾病的新临床试验。 CS是50岁以下患者中第三大最常见的恶性骨肿瘤,是外科手术治疗的疾病,常规不接受化学疗法治疗。如前所述,参与临床研究,治疗,生物学,登记或癌症控制被认为是所有患者的目标,实际上,这是患癌症儿童的“护理标准”。

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