The role of hepatic lipase in lipoprotein metabolism and atherosclerosis.

Santamarina-Fojo S; Haudenschild C; Amar M

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The role of hepatic lipase in lipoprotein metabolism and atherosclerosis.

机译：肝脂肪酶在脂蛋白代谢和动脉粥样硬化中的作用。

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In addition to its traditional role in the hydrolysis of lipoprotein triglycerides and phospholipids, recent studies have implicated hepatic lipase in other aspects of cellular lipid and/or lipoprotein metabolism and atherosclerosis. Hepatic lipase may serve as a ligand that mediates the interaction of lipoproteins to cell surface receptors and/or proteoglycans as well as modulating aortic lesion development in different animal models. Over the past several years significant advances have been made in our understanding of new, alternative mechanisms by which hepatic lipase may modulate lipoprotein metabolism and the development of atherosclerosis in vivo.

机译：除了其在脂蛋白甘油三酸酯和磷脂水解中的传统作用外，最近的研究还表明肝脂酶还涉及细胞脂质和/或脂蛋白代谢和动脉粥样硬化的其他方面。肝脂肪酶可以充当配体，介导脂蛋白与细胞表面受体和/或蛋白聚糖的相互作用，并调节不同动物模型中的主动脉病变发展。在过去的几年中，我们对新的替代机制的了解取得了重大进展，肝脏脂肪酶可通过这种新机制来调节脂蛋白的代谢和体内动脉粥样硬化的发展。

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《Current opinion in lipidology》 |1998年第3期|共9页
作者
Santamarina-Fojo S; Haudenschild C; Amar M;
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原文格式 PDF
正文语种 eng
中图分类生物化学;
关键词
Atherosclerosis; Lipase; Lipoproteins; Liver; Lipids; Proteoglycans; Receptors; Cell Surface; 动脉粥样硬化; 脂酶; 脂蛋白类; 肝;

机译：Atherosclerosis;Lipase;Lipoproteins;Liver;Lipids;Proteoglycans;Receptors;Cell Surface;动脉粥样硬化;脂酶;脂蛋白类;肝;

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1. The role of hepatic lipase in lipoprotein metabolism and atherosclerosis. [J] . Santamarina-Fojo S, Haudenschild C, Amar M Current opinion in lipidology . 1998,第3期

机译：肝脂肪酶在脂蛋白代谢和动脉粥样硬化中的作用。
2. Role of macrophage-derived lipoprotein lipase in lipoprotein metabolism and atherosclerosis. [J] . Van Eck-M, Zimmermann R, Groot PH, Arteriosclerosis, thrombosis, and vascular biology . 2000,第9期

机译：巨噬细胞源性脂蛋白脂肪酶在脂蛋白代谢和动脉粥样硬化中的作用。
3. The role of plasma lipoprotein lipase, hepatic lipase and GPIHBP1 in the metabolism of remnant lipoproteins and small dense LDL in patients with coronary artery disease [J] . Yuji Muraba, Takafumi Koga, Yohnosuke Shimomura, Clinica chimica acta: International journal of clinical chemistry and applied molecular biology . 2018,第期

机译：血浆脂蛋白脂肪酶，肝脂肪酶和GPIHBP1在冠状动脉疾病患者中残留脂蛋白和小致密LDL的代谢中的作用
4. The role of feeding regimens in regulating metabolism of broiler breeders: hepatic lipid metabolism, plasma hormones and metabolites [C] . M. de Beer, R. W. Rosebrough, B.A. Russell, International Symposium on Energy and Protein Metabolism and Nutrition . 2007

机译：喂养方案在调节肉鸡育种者的代谢中的作用：肝脂代谢，血浆激素和代谢物
5. THE ROLE OF HEPATIC LIPASE IN THE DELIVERY OF HIGH DENSITY LIPOPROTEIN CHOLESTEROL TO CELLS IN CULTURE. [D] . BAMBERGER, MARK JOSEPH. 1984

机译：肝脂肪酶在高密度脂蛋白胆固醇向细胞中传递中的作用。
6. Impact of Combined Deficiency of Hepatic Lipase and Endothelial Lipase on the Metabolism of Both High-Density Lipoproteins and Apolipoprotein B–Containing Lipoproteins [O] . Robert J. Brown, William R. Lagor, Sandhya Sankaranaravanan, -1

机译：肝脂肪酶和内皮脂肪酶组合缺乏对高密度脂蛋白和载脂蛋白B型脂蛋白的代谢的影响
7. Effects of heparin infusion on plasma lipoproteins in subjects with lipoprotein lipase deficiency: Evidence for a role of hepatic endothelial lipase in the metabolism of high-density lipoprotein subfractions in man [O] . 1983

机译：肝素输注对脂蛋白脂肪酶缺乏症患者血浆脂蛋白的影响：肝内皮脂肪酶在人高密度脂蛋白亚型代谢中的作用的证据

The role of hepatic lipase in lipoprotein metabolism and atherosclerosis.

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