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Seroprevalence of varicella zoster virus among pregnant women in Hong Kong: Comparison with self-reported history

机译:香港孕妇中毒液疱疹病毒的Seroprevalence:与自我报告的历史比较

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摘要

Objective: To compare seroprevalence (serum IgG titre) with self-reported history of varicella zoster virus (VZV) infection among pregnant women in Hong Kong. Methods: Pregnant women undergoing first trimester Down screening over a 3-months period were recruited for the study. Results: Positive immunity was found in 477 (95.4%) of the 500 recruited women, and those with positive, negative, or uncertain history of infection had similarly high seroprevalence (96.4, 90.5, 95.9% respectively). The mean age of infection from self-recalled history was 8.61 (SD 4.69) years, and only 3% recalled infection after age 18. Insufficient knowledge on the disease and vaccination was demonstrated. Conclusions: Despite the absence of a routine vaccination programme,VZV immunity was high among pregnant women, the majority being infected during childhood and infection above age 18 was very rare. Hence, universal antenatal screening or vaccination for all women in the reproductive age would not be cost-effective in Hong Kong.
机译:目的:比较香港孕妇的孕妇血清素泽氏病毒(VZV)感染的自我报告史(血清IgG Titre)。方法:招募在3个月内接受妊娠早期筛查的孕妇,为这项研究招募。结果:在500名招募妇女的477名(95.4%)中发现了阳性免疫,感染率阳性,阴性或不确定史的人具有同样高的血清透析(96.4,90.5,95.9%)。自回忆历史的平均感染年龄是8.61(SD 4.69)岁,但在18岁后只有3%的召回感染。对疾病和疫苗接种的知识不足。结论:尽管缺乏常规疫苗接种程序,但VZV免疫力在孕妇中很高,患儿感染儿童和18岁以上的感染非常罕见。因此,生殖年龄所有妇女的普遍产前筛查或疫苗接种在香港不会具有成本效益。

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  • 来源
    《Vaccine》 |2011年第46期|共3页
  • 作者单位

    Department of Obstetrics &

    Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong PR China;

    Department of Obstetrics &

    Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong PR China;

    Department of Obstetrics &

    Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong PR China;

    Department of Obstetrics &

    Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong PR China;

    Department of Obstetrics &

    Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong PR China;

    Department of Microbiology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong PR China;

    Department of Microbiology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong PR China;

    Department of Obstetrics &

    Gynaecology The Chinese University of Hong Kong Prince of Wales Hospital Shatin Hong Kong PR China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 医学免疫学;
  • 关键词

    Chickenpox; Pregnancy; Vaccination; Varicella;

    机译:水痘;妊娠;疫苗接种;水痘;

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