Incorporation of RG1 epitope into HPV16L1-VLP does not compromise L1-specific immunity

Schellenbacher C.; Huber B.; Skoll M.; Shafti-Keramat S.; Roden R. B. S.; Kirnbauer R.

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Incorporation of RG1 epitope into HPV16L1-VLP does not compromise L1-specific immunity

机译：将RG1表位掺入HPV16L1-VLP不会损害L1特异性免疫力

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The candidate pan-Human Papillomavirus (HPV) vaccine RG1-VLP are HPV16 major capsid protein L1 virus-like-particles (VLP) comprising a type-common epitope of HPV16 minor capsid protein L2 (RG1; aa17-36). Vaccinations have previously demonstrated efficacy against genital high-risk (hr), low-risk (1r) and cutaneous HPV.

机译：候选泛人乳头瘤病毒（HPV）疫苗RG1-VLP是HPV16主要衣壳蛋白L1病毒样颗粒（VLP），其包含HPV16次胶囊蛋白L2的常见表位（RG1; AA17-36）。疫苗接种以前表现出对生殖器高风险（HR），低风险（1R）和皮肤HPV的疗效。

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来源
《Vaccine》 |2019年第27期|共6页
作者
Schellenbacher C.; Huber B.; Skoll M.; Shafti-Keramat S.; Roden R. B. S.; Kirnbauer R.;
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作者单位

Med Univ Vienna MUW Dept Dermatol Vienna Austria;

Med Univ Vienna MUW Dept Dermatol Vienna Austria;

Med Univ Vienna MUW Dept Dermatol Vienna Austria;

Med Univ Vienna MUW Dept Dermatol Vienna Austria;

Johns Hopkins Univ Dept Pathol Baltimore MD USA;

Med Univ Vienna MUW Dept Dermatol Vienna Austria;

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正文语种 eng
中图分类医学免疫学;
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1. Incorporation of RG1 epitope into HPV16L1-VLP does not compromise L1-specific immunity [J] . Schellenbacher C., Huber B., Skoll M., Vaccine . 2019,第27期

机译：将RG1表位掺入HPV16L1-VLP不会损害L1特异性免疫力
2. Incorporation of T-cell epitopes from tetanus and diphtheria toxoids into in-silico-designed hypoallergenic vaccine may enhance the protective immune response against allergens [J] . Ali Ghasemi, Reza Falak, Mohsen Mohammadi, Iranian Journal of Basic Medical Sciences . 2020,第5期

机译：将T细胞和白喉类毒素的T细胞表位掺入硅设计中，可以增强对过敏原的保护性免疫应答
3. A membrane penetrating multiple antigen peptide (MAP) incorporating ovalbumin CD8 epitope induces potent immune responses in mice. [J] . Brooks NA, Pouniotis DS, Sheng KC, Biochimica et biophysica acta. Biomembranes . 2010,第12期

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4. Heat shock protein 70/alpha-fetoprotein epitope peptide induced specific immunity against hepatocarcinoma [C] . Bing Xu, Xiaoping Wang, Xiaojun Ma International Symposium on Application of Materials Science and Energy Materials . 2019

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5. Focusing immune response on key neutralizing epitopes of HIV-1 through immune complex vaccination. [D] . Agrawal, Aditi. 2016

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6. Incorporation of RG1 epitope concatemers into a self-adjuvanting Flagellin-L2 vaccine broaden durable protection against cutaneous challenge with diverse human papillomavirus genotypes [O] . Kirill Kalnin, Sudha Chivukula, Timothy Tibbitts, -1

机译：将RG1表位连接物掺入自佐剂鞭毛蛋白L2疫苗中可扩展针对多种人类乳头瘤病毒基因型对皮肤攻击的持久保护
7. 375. Incorporation of Pseudomonas aeruginosa Epitope in Novel Adenovirus Fiber Loops To Circumvent Anti-Adenovirus Immunity and To Induce Protective Immunity [O] . 2012

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Incorporation of RG1 epitope into HPV16L1-VLP does not compromise L1-specific immunity

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