Haemophilus influenzae-protein D specific antibody correlate with protection against acute otitis media in young children

Almudevar Anthony; Pichichero Michael E.

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Haemophilus influenzae-protein D specific antibody correlate with protection against acute otitis media in young children

机译：嗜血杆菌嗜血杆菌蛋白D特异性抗体与幼儿急性中耳介质的保护相关

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Background: Haemophilus influenzae (Hi) causes respiratory infections and pathogenesis of this microbe begins in the human nasopharynx (NP). The objective of this study was to assess the correlation of NP colonization-induced serum antibody levels to Hi protein D with risk of acute otitis media (AOM) in children &2 yr.

机译：背景：嗜血杆菌（HI）引起呼吸道感染和这种微生物的发病机制在人鼻咽（NP）中。本研究的目的是评估NP殖民化诱导的血清抗体水平与儿童急性中耳炎（AOM）风险的血清抗体水平与儿童急性中耳炎的风险的相关性; LT; 2 YR。

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《Vaccine》 |2018年第9期|共3页
作者
Almudevar Anthony; Pichichero Michael E.;
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作者单位

Univ Rochester Med Ctr Dept Biostat &

Computat Biol Rochester NY 14642 USA;

Rochester Gen Hosp Res Inst Ctr Infect Dis &

Immunol 1425 Portland Ave Rochester NY 14621 USA;

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原文格式 PDF
正文语种 eng
中图分类医学免疫学;
关键词
Haemophilus influenzae; Correlate of protection; Antibody response;

机译：嗜血杆菌嗜血杆菌;相关保护;抗体反应;

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1. Haemophilus influenzae-protein D specific antibody correlate with protection against acute otitis media in young children [J] . Almudevar Anthony, Pichichero Michael E. Vaccine . 2018,第9期

机译：嗜血杆菌嗜血杆菌蛋白D特异性抗体与幼儿急性中耳介质的保护相关
2. Serum antibody response to three non-typeable Haemophilus influenzae outer membrane proteins during acute otitis media and nasopharyngeal colonization in otitis prone and non-otitis prone children [J] . Kaur Ravinder, Casey Janet R., Pichichero Michael E. . Vaccine . 2011,第5期

机译：易中耳和非中耳炎儿童在急性中耳炎和鼻咽部定植过程中对三种不可分型流感嗜血杆菌外膜蛋白的血清抗体反应
3. Bactericidal antibody response against P6, protein D, and OMP26 of nontypeable Haemophilus influenzae after acute otitis media in otitis-prone children [J] . KhanM.N., KaurR., PichicheroM.E. FEMS immunology and medical microbiology . 2012,第3期

机译：易中耳炎儿童急性中耳炎后针对非分型流感嗜血杆菌P6，蛋白D和OMP26的杀菌抗体反应
4. Microbiology of acute otitis media with perforation (AOMwiP) in Aboriginal children living in remote communities-monitoring the impact of 7-valent pneumococcal conjugate vaccine (7vPCV) [C] . Amanda Leach, Grant MacKenzie, Kim Hare, Lancefield International Symposium on Streptococci and Streptococcal Diseases . 2006

机译：具有穿孔（Aomwip）的急性中耳炎的微生物学，在偏远社区生活在偏远社区中的土着儿童 - 监测7价肺炎球菌缀合物疫苗的影响（7VPCV）
5. Protein Vaccines Against Acute Otitis Media Caused by Nontypeable Haemophilus influenzae in a Murine Model [D] . Zavorin, Mark. 2018

机译：蛋白质疫苗针对鼠模型中的不可迁移血液血液嗜血杆菌引起的急性中耳炎
6. Haemophilusinfluenzae-Protein D Specific Antibody Correlate with Protection against Acute Otitis Media in Young Children [O] . Anthony Almudevar, Michael E Pichichero -1

机译：嗜血杆菌流感蛋白D特异性抗体与儿童急性中耳炎的保护相关
7. Serum antibody response to three non-typeable Haemophilus influenzae outer membrane proteins during acute otitis media and nasopharyngeal colonization in otitis prone and non-otitis prone children [O] . Ravinder Kaur, Janet R. Casey, Michael E. Pichichero 2011

机译：在急性中耳炎培养基和鼻咽癌中鼻咽癌的血清抗体反应响应三种非易形的血液渗透型外膜蛋白和鼻咽癌的鼻咽癌和非耳炎
8. Otitis Media with Effusion in Young Children. Clinical Practice Guideline Number12; Managing Otitis Media with Effusion in Young Children. Quick Reference Guide for Clinicians Number 12; Middle Ear Fluid in Young Children: Consumer Version. Clinical Pract [R] . 1994

机译：中耳炎患儿的中耳炎。临床实践指南第12号;青少年积液治疗中耳炎。第12号临床医生快速参考指南;幼儿中耳液：消费者版。临床实践

Haemophilus influenzae-protein D specific antibody correlate with protection against acute otitis media in young children

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