...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Dalton transactions: An international journal of inorganic chemistry >A selective hydrolytic and restructuring approach through a Schiff base design on a coumarin platform for 'turn-on' fluorogenic sensing of Zn2+
【24h】

A selective hydrolytic and restructuring approach through a Schiff base design on a coumarin platform for 'turn-on' fluorogenic sensing of Zn2+

机译：一种通过秀丽血管平台设计的选择性水解和重组方法，用于“开启”ZN2 +荧光传感

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A new Schiff base, CMD, designed based on a coumarin platform was synthesized and fully characterized through single crystal X-ray diffraction studies. CMD underwent selective Zn2+-triggered hydrolysis in ethanolic medium followed by restructuring of its fragments, resulting in a "turn-on" green fluorogenic response. This response was confirmed through various physico-chemical measurements along with single crystal X-ray diffraction studies. This selective hydrolytic fluorogenic event was exploited for the successful optical detection and live cell imaging of Zn2+ in SiHa cells. The above restructured products were characterized as two new Schiff bases, viz. CM and NSA, of which NSA was highly fluorescent (green). Hence, the formation of this green fluorogenic product accounted for the above fluorogenic "turn-on" sensing of Zn2+ with a sub-nanomolar detection limit. Spectroscopic evidence along with mass determinations indicated that the Zn-CMD ensemble took the form of CM-Zn-CM in solution, supporting our above proposal of hydrolysis and restructuring. However, the X-ray diffraction studies of the Zn-CMD ensemble further revealed it to consist of NSA and CM-Zn-CM', where CM' is yet another new Schiff base formed in situ during the process of developing single crystals.
机译：基于Coumarin平台设计的新的Schiff基底CMD是通过单晶X射线衍射研究的合成和完全表征。 CMD在乙醇介质中接受了选择性Zn2 + - 触发水解，然后重组其片段，导致“开启”绿色荧光反应。通过各种物理化学测量和单晶X射线衍射研究进行确认该响应。这种选择性水解荧光事件被利用在Siha细胞中的Zn2 +的成功检测和活细胞成像。上述重组产品的特征是两个新的Schiff Bases，Viz。厘米和NSA，其中NSA高度荧光（绿色）。因此，这种绿色荧光产物的形成占Zn2 +的上述荧光的“开启”感测，具有亚纳米罗勒检测极限。光谱依据以及质量测定表明，Zn-CMD系列采用溶液中的CM-Zn-CM的形式，支持我们上述水解和重组的提议。然而，Zn-CMD集合的X射线衍射研究进一步揭示了由NSA和CM-Zn-cm'组成，其中Cm'是在开发单晶的过程中原位形成的另一个新的Schiff碱。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号