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首页> 外文期刊>Diabetes care >Seasonal Variations in the Achievement of Guideline Targets for HbA(1c), Blood Pressure, and Cholesterol Among Patients With Type 2 Diabetes: A Nationwide Population-Based Study (ABC Study: JDDM49)
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Seasonal Variations in the Achievement of Guideline Targets for HbA(1c), Blood Pressure, and Cholesterol Among Patients With Type 2 Diabetes: A Nationwide Population-Based Study (ABC Study: JDDM49)

机译：2型糖尿病患者的HBA（1C），血压和胆固醇的季节性变异：基于全国的人口的研究（ABC研究：JDDM49）

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摘要

OBJECTIVE Precise monthly achievement rates for reaching guideline targets for HbA(1c), blood pressure (BP), and lipid levels remain unknown. We evaluated achievement rates on a monthly basis in persons with type 2 diabetes mellitus (T2DM) and explored related factors. RESEARCH DESIGN AND METHODS This retrospective study initially analyzed data on 104,601 persons with T2DM throughout Japan. Patients whose HbA(1c), BP, and LDL cholesterol were measured >= 12 times during a 24-month period were included. We evaluated monthly achievement rates. Achieved targets were defined as HbA(1c) = 65 years (odds ratio 0.47 [95% CI 0.34-0.63]) was independently related to decreased achievement rates for SBP, BMI >= 25 kg/m(2) (BMI 25-30 kg/m(2), 0.45 [0.29-0.70]; BMI >= 30 kg/m(2), 0.35 [0.22-0.57]), and diabetes duration >= 10 years (0.53 [0.37-0.76]) were independently related to lower achievement rates for HbA(1c). Insulin use and sulfonylurea use were independently associated with the decreased all ABC achievement rates in both summer and winter. CONCLUSIONS The all ABC achievement rate for guideline targets changed on a monthly basis. Seasonal variations in the all ABC achievement rate should be considered when managing T2DM in ordinary clinical practices.
机译：客观精确的月度成就率用于达到HBA（1C），血压（BP）和脂质水平的指南靶向仍然未知。我们根据2型糖尿病（T2DM）和探索相关因素的人每月评估成就率。研究设计与方法本回顾性研究最初分析了在日本整个T2DM的104,601人上的数据。在包括24个月内测量HBA（1C），BP和LDL胆固醇的患者= 12次。我们评估了每月成就率。达到的靶标被定义为HBA（1c）= 65岁（0.47 [95％CI 0.34-0.63]）与SBP，BMI> = 25kg / m（2）（BMI 25-30）（BMI 25-30）（BMI 25-30）独立相关kg / m（2），0.45 [0.29-0.70]; BMI> = 30kg / m（2），0.35 [0.22-0.57]），糖尿病持续时间> = 10年（0.53 [0.37-0.76]）独立与HBA（1C）的较低成就率相关。胰岛素使用和磺酰脲类用途与夏季和冬季的所有ABC成就率下降无关。结论指南目标的所有ABC成就率为每月更改。在普通临床实践中管理T2DM时，应考虑所有ABC成就率的季节变化。

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  • 来源
    《Diabetes care》 |2019年第5期|共8页
  • 作者

    Sakamoto Masaya; Matsutani Daisuke; Minato Soichiro; Tsujimoto Yuki; Kayama Yosuke; Takeda Norihiko; Ichikawa Seiichi; Horiuchi Ryuzo; Utsunomiya Kazunori; Nishikawa Masako;

  • 作者单位

    Jikei Univ Sch Med Dept Internal Med Div Diabet Metab &

    Endocrinol Minato Ku Tokyo Japan;

    Jikei Univ Sch Med Dept Internal Med Div Diabet Metab &

    Endocrinol Minato Ku Tokyo Japan;

    Jikei Univ Sch Med Dept Internal Med Div Diabet Metab &

    Endocrinol Minato Ku Tokyo Japan;

    Jikei Univ Sch Med Dept Internal Med Div Diabet Metab &

    Endocrinol Minato Ku Tokyo Japan;

    Jikei Univ Sch Med Dept Cardiol Minato Ku Tokyo Japan;

    Univ Tokyo Grad Sch Med Dept Cardiovasc Med Tokyo Japan;

    Tsuruoka Kyoritsu Hosp Dept Cardiol Tsuruoka Yamagata Japan;

    Tsuruoka Kyoritsu Hosp Dept Pathol Tsuruoka Yamagata Japan;

    Jikei Univ Sch Med Dept Internal Med Div Diabet Metab &

    Endocrinol Minato Ku Tokyo Japan;

    Jikei Univ Sch Med Clin Res Support Ctr Minato Ku Tokyo Japan;

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  • 正文语种 eng
  • 中图分类 内分泌腺疾病及代谢病;
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