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首页> 外文期刊>Current Genetics: Eukaryotes with Emphasis on Yeasts, Fungi, Mitochondria, Plastids >Bacterial protein acetylation: new discoveries unanswered questions
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Bacterial protein acetylation: new discoveries unanswered questions

机译:细菌蛋白乙酰化:新发现未解决的问题

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摘要

N epsilon-acetylation is emerging as an abundant post-translational modification of bacterial proteins. Two mechanisms have been identified: one is enzymatic, dependent on an acetyltransferase and acetyl-coenzyme A; the other is non-enzymatic and depends on the reactivity of acetyl phosphate. Some, but not most, of those acetylations are reversed by deacetylases. This review will briefly describe the current status of the field and raise questions that need answering.
机译:Nε-乙酰化正作为细菌蛋白质的大量翻译后修饰而出现。已经确定了两种机理:一种是酶促的,依赖于乙酰转移酶和乙酰辅酶A;另一种是酶促的。另一种是非酶促的,取决于乙酰磷酸的反应性。这些乙酰化中的一些(但不是大多数)可以通过脱乙酰基酶逆转。本文将简要介绍该领域的现状,并提出需要回答的问题。

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