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Comorbidity of psychiatric and substance use disorders in the United States: Current issues and findings from the NESARC

机译:美国精神病和药物滥用疾病的合并症:NESARC的最新问题和发现

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摘要

Purpose of Review: The comorbidity between psychiatric and substance use disorders remains an important phenomenon to understand, and an active area of investigation. The purpose of this review is to highlight key 2011 issues and novel findings on psychiatric and substance disorders comorbidity from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a large national survey of the US general population. Recent Findings: Topics of active investigation included the internalizing/externalizing meta-structure of common mental disorders; the 10 Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) personality disorders; the 3-year incidence and persistence of disorders; treatment of major depression; and many other topics not as easily categorized. Summary: Meta-structure may increasingly offer a parsimonious way of addressing comorbidity, although adding new disorders adds complexity and the value of etiologic analyses utilizing broad dimensions of psychopathology rather than individual disorders is not yet fully known. Expanding the range of personality disorders beyond antisocial personality disorder appears essential in understanding the incidence and persistence of substance use disorders. Substance use disorders have low rates of treatment relative to major depression, but increase the likelihood of depression treatment among comorbid cases, a phenomenon that needs to be understood. These comorbidity studies provide much novel information, and indicate many potentially fruitful directions for new research.
机译:审查目的:精神病和药物滥用疾病之间的合并症仍然是一个重要的现象,需要了解,并且是一个活跃的研究领域。这篇综述的目的在于重点介绍2011年的主要问题以及《美国国家酒精与相关疾病流行病学调查》(NESARC)中有关精神病和药物障碍合并症的新发现,这是一项针对美国普通人群的大型国家调查。最新发现:积极研究的主题包括常见精神障碍的内在化/外在化元结构。 《精神障碍诊断和统计手册》第10版,第四版(DSM-IV);疾病的三年发病率和持续性;重度抑郁症的治疗;以及其他许多不容易分类的主题。简介:尽管增加新的疾病会增加复杂性,并且利用心理病理学而非个体疾病的广泛维度进行病因分析的价值尚不完全清楚,但元结构可能会越来越多地提供一种解决合并症的方法。将人格障碍的范围扩大到反社会人格障碍之外,对于理解药物滥用障碍的发生和持续性看来至关重要。与重度抑郁症相比,物质使用障碍的治疗率较低,但是在合并症中,抑郁症治疗的可能性增加,这是需要理解的现象。这些合并症研究提供了许多新颖的信息,并为新研究指明了许多潜在的富有成果的方向。

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