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首页> 外文期刊>World neurosurgery >The Effect of Cigarette Smoking on Wound Complications After Single-Level Posterolateral and Interbody Fusion for Spondylolisthesis
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The Effect of Cigarette Smoking on Wound Complications After Single-Level Posterolateral and Interbody Fusion for Spondylolisthesis

机译：香烟吸烟对单级后侧和椎体间融合后伤口并发症的影响

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ObjectiveTo evaluate the impact of cigarette smoking on the development of wound complications, including wound dehiscence, superficial infection, deep infection, or organ space infection, within the first 30 postoperative days in patients undergoing surgery for spondylolisthesis. MethodsThe American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database for the years 2012–2014 was used to identify adult patients who underwent single-level posterolateral fusion (PLF) or interbody fusion for spondylolisthesis. Wound complications occurring within 30 days were compared between current smokers and nonsmokers. ResultsA total of 1688 patients who underwent single-level PLF or interbody fusion for spondylolisthesis were identified, among whom 271 were current smokers (16.1%). The overall wound complication rate was 3.3% for smokers versus 1.8% for nonsmokers (P?= 0.095). When stratified by operative technique, the rate of wound complications was not significantly different between smokers and nonsmokers undergoing PLF (2.4% vs. 2.6%;P?= 1.00); however, smokers who underwent interbody fusion were more likely to experience a wound complication compared with nonsmokers undergoing interbody fusion (3.7% vs. 1.3%;P?= 0.028). On multivariate analysis, smoking was an independent predictor of organ/space infection irrespective of fusion technique used (odds ratio, 15.4; 95% confidence interval, 1.34–175.4;P?= 0.028). ConclusionsThe rate of wound complications was not higher in smokers undergoing PLF alone, but was significantly higher in smokers who underwent interbody fusion. However, multivariate analysis identified smoking as an independent predictor of organ/space infection irrespective of fusion technique used.
机译：ObjectiveTo评估香烟吸烟对伤口并发症的发展的影响，包括脊椎凋亡患者的前30天内的伤口复杂性，包括伤口裂缝，浅表感染，深感染或器官空间感染。方法美国外科医生大学外科医学院2012-2014的国家外科素质改善计划（ACS-NSQIP）数据库用于鉴定接受单层后侧融合（PLF）或椎间体融合的成年患者。在目前的吸烟者和非吸烟者之间比较30天内发生的伤口并发症。结果，鉴定了1688例接受单层PLF或椎间体融合的1688名患者，其中271名是目前吸烟者（16.1％）。对于非吸烟者而言，体外伤口并发症率为3.3％（P？= 0.095）。当通过手术技术分层时，伤口并发症的速率没有显着差异，吸烟者和遭受PLF的吸烟者（2.4％与2.6％; P？= 1.00）;然而，与经历椎体融合的非莫克者相比，接受椎体融合的吸烟者更有可能经历伤口并发症（3.7％与1.3％; P？= 0.028）。在多变量分析中，吸烟是器官/空间感染的独立预测因子，而不管使用的融合技术（差距，15.4; 95％置信区间，1.34-175.4; p？= 0.028）。结论伤口并发症的速率在伤口率并不高，仅在近融合的吸烟者中显着高。然而，多变量分析确定吸烟作为器官/空间感染的独立预测因子，而不管使用的融合技术如何。

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