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Engineered and designed peptide-based fibrous biomaterials

机译:设计和设计基于肽的纤维生物材料

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摘要

Our increasing understanding of peptide and protein folding and assembly raises new possibilities for engineering novel self-assembling supramolecular structures and bio-inspired materials. Here we focus on peptides designed de novo, and natural systems that have been engineered to form extended protein fibres. Potential applications of such assemblies include the preparation of functionalised biomaterials for the development of new diagnostic devices, scaffolds to recruit cells for cell/tissue engineering, and templates for the assembly of inorganic materials.
机译:我们对肽和蛋白质折叠与组装的日益了解为工程新的自组装超分子结构和生物启发性材料的开发提供了新的可能性。在这里,我们专注于从头设计的肽,以及经过工程改造以形成延伸蛋白纤维的天然系统。这种组件的潜在应用包括制备功能性生物材料以开发新的诊断设备,为细胞/组织工程募集细胞的支架以及用于无机材料组装的模板。

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