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首页> 外文期刊>Biosciences Biotechnology Research Asia >Coronary Risk Factors in Patients with Coronary Artery Ectasia : A Case-Control Study from Iran
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Coronary Risk Factors in Patients with Coronary Artery Ectasia : A Case-Control Study from Iran

机译：冠状动脉扩张症患者的冠状动脉危险因素：来自伊朗的病例对照研究

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Coronary artery ectasia is a rare finding in angiography. We investigated the prevalence of coronary artery ectasia and assessed cardiovascular risk factors as probable influencing factors in this disease in our region. This study was conducted from October 2007 to March 2010 on 2500 patients visiting Imam Reza and Qaem and Razavi hospitals, Mashhad, Iran who had chest pain and were selected for angiographic studies. The study was based on reviewing angiographic films besides filling in questionnaires. 103 coronary artery ectasia cases showing 4% prevalence for this kind of coronary involvement were selected as the study group and compared with 62 patients with atherosclerosis and no ectasia as the control group. Mean age of the study and control group was 57.6 and 54.1yrs, respectively indicating a statistically significant difference (p=0.032). The study and control groups showed no significant difference based on sex, smoking history and mean Body Mass Index (BMI). However, a BMI above 25 had asignificantly higher prevalence in the study group (p=0.036). Mean hs-CRP and homocystein levels were 3.4 and 11.8 in the study group and 2.3 and 8.3 in the control group, respectively, both revealing a significant difference (p=0.002, p<0.001). Hyperlipidemia in ectasia patients in comparison to controls was significantly more prevalent (p=0.001). The prevalence of coronary artery ectasia was 4% and cardiovascular risk factors in ectasia cases included: hyperlipidemia, high hs-CRP, and homocystein.
机译：冠状动脉扩张在血管造影术中是罕见的发现。我们调查了冠状动脉扩张的患病率，并将心血管危险因素评估为该地区本病的可能影响因素。该研究于2007年10月至2010年3月对2500名就诊于伊朗马什哈德的Imam Reza和Qaem和Razavi医院的患有胸痛并被选择进行血管造影研究的患者进行。该研究是基于对血管造影胶片的检查，以及填写调查表的基础。选择103例这种冠状动脉受累患病率4％的冠状动脉扩张症患者作为研究组，并与62例无扩张症的动脉粥样硬化患者进行比较。研究组和对照组的平均年龄分别为57.6岁和54.1岁，表明具有统计学显着性差异（p = 0.032）。研究组和对照组在性别，吸烟史和平均体重指数（BMI）方面均无显着差异。但是，研究组的BMI高于25的患病率明显更高（p = 0.036）。研究组的平均hs-CRP和高半胱氨酸水平分别为3.4和11.8，对照组为2.3和8.3，两者均显示出显着差异（p = 0.002，p <0.001）。与对照组相比，扩张期患者的高脂血症更为普遍（p = 0.001）。冠状动脉扩张症的患病率为4％，扩张症病例的心血管危险因素包括：高脂血症，高hs-CRP和高半胱氨酸。

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