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首页> 外文期刊>Journal of Neurophysiology >High-definition tDCS to the right temporoparietal junction modulates slow-wave resting state power and coherence in healthy adults
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High-definition tDCS to the right temporoparietal junction modulates slow-wave resting state power and coherence in healthy adults

机译:高清TDC对右临时锁定结调制了健康成年人的慢波休息状态和连贯性

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摘要

The right temporoparietal junction (rTPJ) is a multisensory integration hub that is increasingly utilized as a target of stimulation studies exploring its rich functional network roles and potential clinical applications. While transcranial direct current stimulation (tDCS) is frequently employed in such studies, there is still relatively little known regarding its local and network neurophysiological effects, particularly at important nonmotor sites such as the rTPJ. The current study applied either anodal, cathodal, or sham high-definition tDCS to the rTPJ of 53 healthy participants and used offline EEG to assess the impacts of stimulation on resting state (eyes open and eyes closed) band power and coherence. Temporoparietal and central region delta power was increased after anodal stimulation (the latter trend only), whereas cathodal stimulation increased frontal region delta and theta power. Increased coherence between right and left temporoparietal regions was also observed after anodal stimulation. All significant effects occurred in the eyes open condition. These findings are discussed with reference to domain general and mechanistic theories of rTPJ function. Low-frequency oscillatory activity may exert long-range inhibitory network influences that enable switching between and integration of endogenous/exogenous processing streams.
机译:正确的临时交界处(RTPJ)是一种多福管集成集线器,越来越多地利用作为探索其丰富的功能网络角色和潜在临床应用的刺激研究的目标。在这种研究中经常使用经颅直流刺激(TDC),仍然对其局部和网络神经生理效应仍然相对较少,特别是在诸如RTPJ的重要的非运动位点。目前的研究应用了Anodal,Cathodal或假的高清TDC到53个健康参与者的RTPJ,并使用离线EEG来评估刺激对休息状态的影响(眼睛睁开眼睛闭合)乐队能力和连贯性。在阳极刺激(仅次于趋势)后,临时迁移和中央区域三角洲电力增加,而阴极刺激增加了正面区域三角洲和THETA权力。在阳极刺激后,还观察到右侧和左侧临时区域之间的相干性增加。所有显着影响发生在眼睛打开状态。参考RTPJ函数的域一般和机械理论讨论这些发现。低频振荡活动可能发挥远程抑制网络的影响,使得内源/外源性加工流之间的切换和整合。

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