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首页> 外文期刊>Chronobiology international >KiSS-1: A likely candidate for the photoperiodic control of reproduction in seasonal breeders
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KiSS-1: A likely candidate for the photoperiodic control of reproduction in seasonal breeders

机译：KiSS-1：季节性育种者光周期控制繁殖的可能候选者

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摘要

In seasonal species, photoperiod exerts tight regulation of reproduction to ensure that birth occurs at the most favorable time of yr. A distinct photoneuroendocrine circuit composed of the retina, suprachiasmatic nucleus (SCN) of the hypothalamus, and pineal gland transduces daylength into a rhythmic secretion of melatonin. The duration of the night-time rise of this hormone conveys daylength information to the organism. Melatonin is known to mediate the control of seasonal reproduction, but how it modulates sexual activity is far from understood. Recent data indicate that the product of the KiSS-1 gene is a potent stimulator of the hypothalamic-pituitary-gonadal axis and may play, together with its receptor GPR54, a central role in the neuroendocrine regulation of gonadotropin secretion. This article briefly reviews these findings and presents arguments that KiSS-1 could take part in the seasonal control of reproduction.
机译：在季节性物种中，光周期会严格控制繁殖，以确保出生在每年最有利的时间进行。独特的光神经内分泌回路由视网膜，下丘脑上视交叉上核（SCN）和松果体组成，将白天转化为褪黑激素的节律性分泌物。这种激素在夜间上升的持续时间将日间信息传达给有机体。众所周知，褪黑素能介导季节性繁殖的控制，但是如何调节性活动却还不清楚。最近的数据表明，KiSS-1基因的产物是下丘脑-垂体-性腺轴的有效刺激剂，可能与其受体GPR54一起在促性腺激素分泌的神经内分泌调节中发挥重要作用。本文简要回顾了这些发现，并提出了有关KiSS-1可以参与繁殖的季节性控制的论点。

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