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首页> 外文期刊>Academic radiology >Diffusion-weighted mr imaging of focal liver lesions in the left and right lobes: Would visual assessment and/or normalization of ADC be useful for overcoming their differences in ADC values resulting from its locations?
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Diffusion-weighted mr imaging of focal liver lesions in the left and right lobes: Would visual assessment and/or normalization of ADC be useful for overcoming their differences in ADC values resulting from its locations?

机译：左右叶局灶性肝病灶的弥散加权mr成像：ADC的视觉评估和/或归一化是否可用于克服其位置导致的ADC值差异？

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We read the recent article entitled "Diffusion-weighted MR Imaging of Focal Liver Lesions in the Left and Right Lobes: Is There a Difference in ADC Values?" by Schmid-Tannwald et al (1) with great interest. They reported a comprehensive, retrospective study to determine possible differences in apparent diffusion coefficient (ADC) values of benign and malignant focal liver lesions (FLLs) and normal ljver parenchyma between left and right hepatic lobes. The authors concluded that ADC values of normal liver parenchyma and benign and malignant FLLs calculated from noncardiac-gated diffusion-weighted (DW) imaging are significantly higher in the left hepatic lobe compared with the right hepatic lobe, and this may be a limitation for characterization of FLLs based on ADC measurements (1). Because we have a special interest for DW imaging in the characterization of FLLs (2—4), we would like to make a contribution regarding possible practical methods" for overcoming this potential limitation in DW irnaging.; In a recent and comprehensive study that aimed to assess the value of visual assessment of signal intensities on b800 s/mm2 DW images and ADC maps in differentiation of benign and malignant FLLs performed by Battal et al (2), benign and malignant FLLs could be differentiated by visual assessment more accurately than by ADC measurement. We think that visual assessment can function as a subjective ADC normalization method. In this technique, the signal intensities of the lesions are compared with the adjacent normal liver parenchyma on the same DW images and ADC maps. Schmid-Tannwald et al (1) reported that measured ADC values of normal left liver lobe parenchyma and benign or malignant focal lesions in the left liver lobe are significantly higher than those located in the right lobe. As an example, in the visual assessment, a left liver lobe focal lesion that has a high ADC value according to that of the identical right lobe can be more accurately evaluated on the background of the adjacent left liver lobe, which has also higher ADC values from the normal right liver lobe and vice versa.
机译：我们阅读了最近的文章“左叶和右叶局灶性肝病灶的弥散加权MR成像：ADC值是否有差异？” Schmid-Tannwald等人（1）引起了极大的兴趣。他们报告了一项全面的回顾性研究，以确定左右肝叶之间的良性和恶性局灶性肝病灶（FLL）和正常肝实质的表观扩散系数（ADC）值可能存在差异。作者得出的结论是，与非右肝叶相比，通过非心动门控弥散加权（DW）成像计算得出的正常肝实质，良性和恶性FLL的ADC值显着更高，这可能是表征的局限性基于ADC测量的FLL的数量（1）。因为我们对DW成像在FLL表征（2-4）方面特别感兴趣，所以我们希望为“克服DW辐照中的这一潜在限制的可能实用方法做出贡献”;在最近的一项综合研究中，为了评估Battal等人（2）对b800 s / mm2 DW图像和ADC图进行信号强度的视觉评估在良恶性FLL鉴别中的价值，通过视觉评估可以比使用MRI更准确地区分良性和恶性FLL ADC测量。我们认为视觉评估可以作为主观ADC归一化方法。在这种技术中，将病变的信号强度与相同的DW图像和ADC图上的相邻正常肝实质进行比较。Schmid-Tannwald等（ 1）报告说，正常左肝叶实质和左肝叶良性或恶性局灶性病变的ADC测得值明显高于右叶。例如，在视觉评估中，可以根据相邻左肝叶的背景更准确地评估根据相同右叶的ADC值较高的左肝叶局灶性病变，来自正常的右肝叶，反之亦然。

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