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首页> 外文期刊>Academic radiology >Diffusion-Weighted MR Imaging of Focal Liver Lesions in the Left and Right Lobes. Is There a Difference in ADC Values?
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Diffusion-Weighted MR Imaging of Focal Liver Lesions in the Left and Right Lobes. Is There a Difference in ADC Values?

机译：左右裂片中焦肝病变的扩散加权MR成像。 ADC值有区别吗？

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摘要

Rationale and Objectives: To determine possible differences between the left and right hepatic lobes in apparent diffusion coefficient (ADC) values of benign and malignant focal liver lesions (FLLs) and normal liver parenchyma. Materials and Methods: Thirty-six patients (16 males, 20 females; mean age 56.8 years) with FLLs of the same etiology in both the left and right hepatic lobes (13 patients with 26 benign FLLs and 23 patients with 46 malignant FLLs) who underwent 1.5T magnetic resonance imaging (MRI) including diffusion-weighted MRI (b values: 0 and 800 seconds/mm) with respiratory gating and without cardiac gating were included in this Health Insurance Portability and Accountability Act-compliant and institutional review board-approved study. ADC values of normal liver parenchyma and FLLs in each hepatic lobe were calculated and compared by using Student's t-test and Wilcoxon signed-rank test, respectively. Results: The mean ADC values of normal liver parenchyma, benign FLLs, and malignant FLLs were significantly higher (P .001, P =.003, and P =.005, respectively) in the left hepatic lobe (1.74 × 10-3, 1.81 × 10-3, and 1.48 × 10-3 mm2/second, respectively) than in the right hepatic lobe (1.48 × 10-3, 1.54 × 10-3, and 1.24 × 10-3 mm2/second, respectively). Conclusion: ADC values of benign and malignant FLLs calculated from noncardiac-gated DW-MRI are significantly higher in the left hepatic lobe compared with the right hepatic lobe. This may be a limitation for characterization of FLLs based on ADC measurements.
机译：理由和目标：确定表观扩散系数（ADC）值的左右肝裂隙与良性和恶性局灶性肝脏病变（FLLS）和正常肝实质之间的可能差异。材料和方法：三十六名患者（16名男性，20名女性;平均56.8岁）在左右肝裂片中具有相同的病因（13名患有26名良性FLLS的患者和23名恶性FLLS患者）在此健康保险便携性和责任行动符合性和制度审查委员会批准的情况下，包括呼吸门控和无心门的扩散加权MRI（B值：0和800秒/ mm），包括扩散加权MRI（B值：0和800秒/ mm），并符合责任行为符合和机构审查委员会批准学习。通过使用学生的T-Test和Wilcoxon签名 - 秩检验，计算并比较每种肝叶中正常肝脏牙髓癌和FLL的ADC值。结果：正常肝实质，良性FLL和恶性FLL的平均ADC值显着高（P <.001，P = .003，P = .005）在左肝叶中（1.74×10- 3,1.81×10-3和1.48×10-3mm2 /秒分别在右肝叶（1.48×10-3，1.54×10-3和1.24×10-3 mm2 /秒）。结论：与右肝叶相比，左肝叶中非心律膜腺门DW-MRI计算的良性和恶性FLL的ADC值显着高。这可能是基于ADC测量的FLL表征FLL的限制。

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