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首页> 外文期刊>Acta biomaterialia >Clinical and pathological effects of different acrylic intracorneal ring segments in corneal additive surgery.
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Clinical and pathological effects of different acrylic intracorneal ring segments in corneal additive surgery.

机译：不同丙烯酸丙烯酸角膜内环段在角膜增生手术中的临床和病理学影响。

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The objective of this work was to evaluate the potential use of less stiff materials based on acrylic copolymers of methyl methacrylate/2-ethylhexyl acrylate (MMA/EHA) as devices to correct, stabilize and improve the effect of poly(methyl methacrylate) (PMMA) intracorneal ring segments. MMA/EHA and PMMA intracorneal ring segments were surgically implanted in the corneas of Lohmann Classic hens. The effects of the intracorneal ring segments were assessed by optical measurements and corneal tolerance was evaluated through biomicroscopic examination over a 90-day observation period and by conventional histology. The experimental results demonstrated that the intracorneal ring segments made of MMA/EHA copolymers provided a significant change in the corneal curvature and an improved in vivo response compared to those obtained for PMMA rings, which was attributed to the higher flexibility of the copolymeric materials, indicating that these systems might be considered suitable as an alternative to those currently used, for application in clinical practice.
机译：这项工作的目的是评估基于甲基丙烯酸甲酯/ 2-丙烯酸乙基己酯的丙烯酸共聚物（MMA / EHA）的刚度较小的材料作为校正，稳定和改善聚甲基丙烯酸甲酯（PMMA）效果的装置的潜在用途）角膜内环段。 MMA / EHA和PMMA角膜内环段通过外科手术植入Lohmann Classic母鸡的角膜中。通过光学测量评估角膜内环段的作用，并通过在90天观察期内的生物显微镜检查和常规组织学评估角膜耐受性。实验结果表明，与PMMA环相比，由MMA / EHA共聚物制成的角膜内环段可显着改变角膜曲率并改善体内反应，这归因于共聚材料的更高柔韧性，这表明这些系统可能被认为适合替代目前在临床实践中使用的系统。

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