首页> 外文期刊>RSC Advances >Sporulaminals A and B: a pair of unusual epimeric spiroaminal derivatives from a marine-derived fungus Paraconiothyrium sporulosum YK-03
【24h】

Sporulaminals A and B: a pair of unusual epimeric spiroaminal derivatives from a marine-derived fungus Paraconiothyrium sporulosum YK-03

机译:Sporulaminals A和B:来自海洋衍生的真菌旁阳离子孢子体YK-03的一对异常的凝皮螺旋体衍生物

获取原文
获取原文并翻译 | 示例
           

摘要

Sporulaminals A (1) and B (2), a pair of unusual epimeric spiroaminal derivatives, bearing a 6/4/5/5 tetracyclic ring system derived from bergamotane sesquiterpenoid, were isolated from a marine-derived fungus Paraconiothyrium sporulosum YK-03. Their structures including the absolute configurations were elucidated by extensive NMR experiments, crystal X-ray diffraction and computational electronic circular dichroism (ECD) method. Furthermore, the epimerization induced by pH, temperature and H2O was revealed, together with the hypothetical biosynthetic pathway.
机译:Sporulaminals A(1)和B(2),一对不寻常的凝皮螺旋体衍生物,携带衍生自培育蛋白倍霉菌萜烯酸的6/4/5/5四环环衍生物,从海洋衍生的真菌亚弧菌孢子体YK-03中分离出衍生的6/4/5/5四环系衍生物。 通过广泛的NMR实验,晶体X射线衍射和计算电子圆形二色(ECD)方法阐明了包括绝对配置的结构。 此外,通过pH,温度和H2O诱导的映射与假设的生物合成途径一起揭示。

著录项

  • 来源
    《RSC Advances》 |2016年第48期|共6页
  • 作者单位

    Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

    Discovery Shenyang 110016 Peoples R China;

    Dalian Univ Sch Life Sci &

    Biotechnol Dalian 116622 Peoples R China;

    Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

    Discovery Shenyang 110016 Peoples R China;

    Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

    Discovery Shenyang 110016 Peoples R China;

    China Acad Chinese Med Sci Inst Chinese Mat Med Beijing 100700 Peoples R China;

    Tianjin Univ Tradit Chinese Med Inst Tradit Chinese Med Tianjin State Key Lab Modern Chinese Med Tianjin 300193 Peoples R China;

    Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

    Discovery Shenyang 110016 Peoples R China;

    Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

    Discovery Shenyang 110016 Peoples R China;

    Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

    Discovery Shenyang 110016 Peoples R China;

    Shenyang Pharmaceut Univ Minist Educ Key Lab Struct Based Drug Design &

    Discovery Shenyang 110016 Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号