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Green synthesis of silver nanoparticles with enhanced antibacterial activity using holocellulose as a substrate and reducing agent

机译:使用Holocellulose作为基材和还原剂具有增强抗菌活性的银纳米粒子的绿色合成

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摘要

Silver nanoparticles (AgNPs) with relatively uniform size and well-defined structure have been synthesized by a hydrothermal method with holocellulose (HC) as a substrate and reducing agent for silver ions. This method was simple, cost-effective and convenient to handle without use of any other stabilizing or reducing agents. The as-prepared HC/Ag nanocomposites exhibited good cytocompatibility to cells and were highly toxic to microorganisms. The antibacterial activity studies were carried out on both Gram-positive S. aureus and Gram-negative E. coli bacteria by a disc diffusion method and an agar dilution method. The important role of HC and the influence of the additional reducing agents (NaBH4 and ascorbic acid) on the products were systematically investigated, and the formation mechanism of HC/Ag nanocomposites was proposed. These results indicate that HC is a good candidate for the preparation of silver-based nanocomposites, and the as-prepared HC/Ag nanocomposites may have potential for use in a wide range of biomedical applications.
机译:具有相对均匀尺寸和明确定义的结构的银纳米颗粒(AgNP)已通过水热法为具有全纤维素(HC)作为银离子的基底和还原剂合成。这种方法简单,成本效益,便于处理,而无需使用任何其他稳定或还原剂。制备的HC / Ag纳米复合材料表现出对细胞的良好细胞相容性,对微生物具有高毒性。通过盘扩散法和琼脂稀释方法对革兰氏阳性的金黄色葡萄球菌和革兰氏阴性大肠杆菌细菌进行抗菌活性研究。 HC的重要作用和附加还原剂(NABH4和抗坏血酸)对产物的影响得到了系统地研究,提出了HC / Ag纳米复合材料的形成机制。这些结果表明,HC是制备基于银基纳米复合材料的良好候选者,并且制备的HC / Ag纳米复合材料可能具有在各种生物医学应用中使用的可能性。

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  • 来源
    《RSC Advances》 |2016年第34期|共9页
  • 作者单位

    Beijing Forestry Univ Coll Mat Sci &

    Technol Beijing Key Lab Lignocellulos Chem Beijing 100083 Peoples R China;

    Beijing Forestry Univ Coll Mat Sci &

    Technol Beijing Key Lab Lignocellulos Chem Beijing 100083 Peoples R China;

    Beijing Forestry Univ Coll Mat Sci &

    Technol Beijing Key Lab Lignocellulos Chem Beijing 100083 Peoples R China;

    Beijing Forestry Univ Coll Mat Sci &

    Technol Beijing Key Lab Lignocellulos Chem Beijing 100083 Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

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