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Interlayer TiO2-HAP composite layer for biomedical applications

机译:用于生物医学应用的层间TiO2-HAP复合层

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摘要

In this paper we discuss the evaluation of a hydroxyapatite [Ca-10(PO4)(6)(OH)(2), HAP] layer developed on titanium by electrophoretic deposition (EPD) and interlayer TiO2 formation on titanium by sintering in air at 800 degrees C for 1 h using electrochemical impedance (EIS) and anodic polarisation studies. The composite layer (HAP-TiO2-Ti) so formed improved the corrosion resistance and the stability of the coatings. The crystallinity, phase composition of the metal surface, HAP coatings, surface morphology and surface topography were characterized by XRD, Raman, FESEM with EDAX and AFM studies respectively. EIS investigations of the composite layer showed high polarization resistance with low capacitance values over the uncoated sample. Similarly, during anodic polarization, high corrosion potential (Ecorr) and low corrosion current density (Icorr) values were obtained for composite layers in comparison with uncoated metal. The in vitro cytotoxicity studies of the coated material were carried out by MTT assay and cell attachment with osteoblast cells. These studies revealed an enhanced cell attachment and proliferation on the composite layer when compared to uncoated metal, which controlled the release of metal ions into the biological system.
机译:本文通过电泳沉积(EPD)和在空气中烧结,探讨通过电泳沉积(EPD)和钛的羟基磷灰石[Ca-10(6)(6)(2),HAP]层的评价,通过烧结在空气中通过烧结钛(EPD)和中间层TiO2形成使用电化学阻抗(EIS)和阳极偏振研究,800℃持续1小时。复合层(HAP-TiO2-Ti)所形成的改善涂层的耐腐蚀性和稳定性。金属表面,HAP涂层,表面形态和表面形态和表面形貌的结晶度,分别具有eDAX和AFM研究的XRD,Raman,eSEM的特征。复合层的EIS调查显示出在未涂覆的样品上具有低电容值的高偏振电阻。类似地,在阳极偏振期间,与未涂覆的金属相比,获得高腐蚀电位(ECORR)和低腐蚀电流密度(ICorr)值。通过MTT测定和具有成骨细胞的细胞附着进行涂覆材料的体外细胞毒性研究。与未涂覆的金属相比,这些研究揭示了复合层上增强的细胞附着和增殖,这将金属离子释放到生物系统中。

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  • 来源
    《RSC Advances》 |2016年第67期|共12页
  • 作者单位

    Rajalakshmi Engn Coll Dept Chem Madras 602105 Tamil Nadu India;

    Rajalakshmi Engn Coll Dept Chem Madras 602105 Tamil Nadu India;

    SRM Easwari Engn Coll Dept Chem Madras 600089 Tamil Nadu India;

    Univ Madras Dept Analyt Chem Guindy Campus Madras 600025 Tamil Nadu India;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;
  • 关键词

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