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A novel solid-state electrochemiluminescence sensor based on a Ru(bpy)(3)(2+)/nano Sm2O3 modified carbon paste electrode for the determination of L-proline

机译:一种基于Ru(BPY)(3)(2 +)/纳米SM2O3改性碳浆料的新型固态电化学荧光传感器,用于测定L-脯氨酸

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摘要

A novel solid-state electrochemiluminescence (ECL) sensor was successfully developed for the determination of L-proline. The ECL signal was generated by a sensitive reaction between Ru(bpy)(3)(2+) and L-proline on a carbon paste electrode (CPE) modified with samarium oxide nanoparticles. The presence of Sm2O3 nanoparticles (NPs) in the carbon paste was found to enhance the electrochemiluminescence signal. Under optimized conditions, a linear relationship between the ECL intensity and the concentration of L-proline was observed in the linear range of 1.00 x 10(-9) to 1.65 x 10(-7) mol L-1 (R-2 = 0.996) with a detection limit of 6.0 x 10(-10) mol L-1 (S/N = 3) and a relative standard deviation of 3.3%. The method was sensitive, selective, simple and successfully applied to the analysis of L-proline in human serum and urine samples.
机译:成功开发了一种新型固态电化学荧光(ECL)传感器以确定L-脯氨酸。 通过氧化钐纳米颗粒改性的碳浆料电极(CPE)上的Ru(BPY)(3)(3)(2+)和L-脯氨酸之间的敏感反应产生ECL信号。 发现SM2O3纳米颗粒(NPS)在碳糊中的存在升高了电化学发光信号。 在优化条件下,在1.00×10(-9)至1.65×10(-7)Mol L-1的线性范围内观察到ECL强度和L-脯氨酸浓度之间的线性关系(R-2 = 0.996 )检测限为6.0×10(-10)mol L-1(S / N = 3),相对标准偏差为3.3%。 该方法敏感,选择性,简单,成功地应用于人血清中L-脯氨酸和尿液样品的分析。

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