• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>RSC Advances >Catalytic applications of {[HMIM]C(NO2)(3)}: as a nano ionic liquid for the synthesis of pyrazole derivatives under green conditions and a mechanistic investigation with a new approach
【24h】

Catalytic applications of {[HMIM]C(NO2)(3)}: as a nano ionic liquid for the synthesis of pyrazole derivatives under green conditions and a mechanistic investigation with a new approach

机译：{[Hmim] C（NO2）（3）}的催化应用为纳米离子液体，用于在绿色条件下合成吡唑衍生物和新方法的机制调查

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Catalytic applications of 1-methylimidazolium trinitromethanide {[HMIM] C(NO2)(3)} as the first nano ionic liquid (NIL) was studied. The described NIL was efficiently tested in the synthesis of 5-amino-pyrazole-4-carbonitrile derivatives in good to excellent yields on the three-component condensation of various aromatic aldehydes, malononitrile and phenylhydrazine at room temperature under solvent-free and ambient conditions. In the next study, 1,4-dihydropyrano-[2,3-c]-pyrazole derivatives were also synthesized via four-component condensation of a good range of aromatic aldehydes, malononitrile, phenylhydrazine and ethyl acetoacetate in the presence of NIL under the same reaction conditions. The described reactions were in good agreement with the green chemistry disciplines and their major advantages are short reaction times, good yields, ease of separation, recycling and reusability of NIL. A new mechanistic approach was proposed for the final step of the pyrazoles synthesis which was supported by theoretical studies.
机译：研究了1-甲基咪唑酯的催化应用{[HMIM] C（NO2）（3）}作为第一纳米离子液体（NIL）。在溶剂和环境条件下，在室温下的三分组分缩合的优异产率优异地，在5-氨基 - 吡唑-4-腈衍生物的合成中有效地测试了所描述的氧化物。在下一步研究中，还通过良好的芳族醛，丙二腈，苯基肼和乙酰乙酸酐在零下的诸如含量的良好范围的芳族醛，丙二腈，乙酰乙酸酯中合成1,4-二氢羟基吡喃-[2,3-C] - 吡唑衍生物相同的反应条件。所述反应与绿色化学学科吻合良好，其主要优势是短暂的反应时间，良好的产量，易分离，零的再循环和可重用性。提出了一种新的机制方法，用于吡唑合成的最后步骤，由理论研究支持。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号