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首页> 外文期刊>Acta Cytologica: The Journal of Clinical Cytology and Cytopathology >Tissue microarrays meet cytopathology.
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Tissue microarrays meet cytopathology.

机译：组织微阵列符合细胞病理学。

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Unlike the sausage technique, TMAs were designed to contain hundreds of individual specimens with a diameter as small as 0.6 mm in an ordered fashion. The great advantage of TMAs was immediately apparent. TMAs allow the analysis of up to 1,000 tumor specimens at a time with at least a 100-fold savings in time and reagents. Since at least 150 sections can be cut from each block, TMAs provide an almost inexhaustible resource that can be shared with other researchers. The original tissue blocks remain preserved to provide a source for future studies rather than being used up for a few molecular analyses. The physical construction of TMAs is comparatively simple, as it requires only an affordable, manually guided device and a skilled operator. There is no shortage of the latter since most technicians (and also some physicians) are manually skilled by training if not by nature. The most critical factors for TMA include careful selection of tissues, marking the representative areas on the original slides andthe collection of the tissue blocks from the archive.
机译：与香肠技术不同，TMA被设计为以有序方式包含数百个直径仅为0.6 mm的单个样本。 TMA的巨大优势显而易见。 TMA可以一次分析多达1,000个肿瘤标本，从而节省至少100倍的时间和试剂。由于每个块至少可以切割150个部分，因此TMA提供了几乎不竭的资源，可以与其他研究人员共享。原始的组织块仍保留下来，为以后的研究提供了来源，而不是被用于一些分子分析。 TMA的物理结构相对简单，因为它只需要价格适中的手动引导设备和熟练的操作人员即可。后者并不乏味，因为如果不是天生的话，大多数技术人员（还有一些医师）都是通过培训来手工操作的。 TMA的最关键因素包括仔细选择组织，在原始载玻片上标记代表性区域以及从档案库中收集组织块。

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