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首页> 外文期刊>Acta Cytologica: The Journal of Clinical Cytology and Cytopathology >Malignant fibrous histiocytoma of the chest wall masquerading as medullary breast carcinoma: a case report.
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Malignant fibrous histiocytoma of the chest wall masquerading as medullary breast carcinoma: a case report.

机译：伪装为髓样乳腺癌的胸壁恶性纤维组织细胞瘤1例。

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BACKGROUND: Cytologic diagnosis of malignant fibrous histiocytoma can be problematic, as these neoplasms are known to mimic multiple other conditions. CASE: A fine needle aspirate from a 60-year-old woman was diagnosed at 2 institutions as medullary carcinoma of the breast. The patient received neo-adjuvant chemoradiotherapy before the tumor war excised. Gross pathologic examination and histomorphology on routine staining were compatible with the cytologic diagnosis. The accurate diagnosis of pleomorphic-storiform-type malignant fibrous histiocytoma was a surprise and was established with immunocytochemical stains. In retrospect, it was thought that clinical and radiologic overlap, creating a high index of suspicion for a breast neoplasm and compounding the cytologic appearance of a medullary carcinoma with spindle cell metaplasia and syncytial cells, was responsible for the error. CONCLUSION: This case highlights a potential cytodiagnostic pitfall and the importance of establishing a definitive tissuediagnosis in the face of equivocal cytologic findings.
机译：背景：恶性纤维组织细胞瘤的细胞学诊断可能存在问题，因为已知这些肿瘤可模仿多种其他疾病。案例：在2个机构中，一名60岁妇女的细针吸出物被诊断为乳房髓样癌。在切除肿瘤战争之前，患者接受了新辅助放化疗。大体病理检查和常规染色的组织形态学与细胞学诊断相符。准确诊断多形性星形样型恶性纤维组织细胞瘤是令人惊讶的，并建立了免疫细胞化学染色法。回顾过去，认为该错误是造成临床和放射学重叠，引起对乳腺肿瘤的高度怀疑以及使髓样癌伴梭形细胞化生和合胞体细胞的细胞学外观复杂化的原因。结论：该病例突出了潜在的细胞诊断的缺陷，并且在面对模棱两可的细胞学发现时强调了确定的组织诊断的重要性。

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