Comparison of cytohistologic techniques in diagnosis of gastroesophageal malignancy.

Batra M; Handa U; Mohan H; Sachdev A

首页> 外文期刊>Acta Cytologica: The Journal of Clinical Cytology and Cytopathology >Comparison of cytohistologic techniques in diagnosis of gastroesophageal malignancy.

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Comparison of cytohistologic techniques in diagnosis of gastroesophageal malignancy.

机译：细胞组织学技术在胃食管恶性肿瘤诊断中的比较。

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OBJECTIVE: To evaluate the diagnostic performance of various endoscopic cytologic techniques, namely, brushing cytology, touch smear cytology and crush cytology, and comparison with concurrent biopsy results in diagnosis of gastroesophageal malignancy. STUDY DESIGN: This prospective study was conducted on 100 patients, with 78 clinically suspected cases of esophageal malignancy and 22 cases of gastric malignancy. RESULTS: The diagnostic accuracy of touch smear in esophageal malignancy was significantly higher (94.12%) than brushing and crush smears (89.71% each), and endoscopic biopsy had the diagnostic accuracy of 88.24%. The diagnostic accuracy of combined brushing and biopsy was 100%; it was 97.06% for touch smears combined with biopsy. In comparison, the diagnostic accuracy in gastric malignancy was 75% for brushing alone, which was significantly lower than touch smear (87.5%) and endoscopic biopsy (87.5%). The diagnostic yield for crush smear was 81.25%. A combination of touch smears and biopsy had a diagnostic yield of 100%; it was 93.75% for combined brushings and biopsy. CONCLUSION: A combination of cytohistologic techniques resulted in a statistically significant increase in the diagnostic yield of gastroesophageal malignancies and thus cytologic techniques may act as adjunct to biopsy histology to increase the diagnostic efficiency.

机译：目的：评估刷内细胞学，触摸涂片细胞学和挤压细胞学等内镜细胞学技术的诊断性能，并与同期活检结果进行比较，以诊断胃食管恶性肿瘤。研究设计：这项前瞻性研究针对100例患者进行，其中78例临床怀疑为食管恶性肿瘤，22例为胃恶性肿瘤。结果：触摸涂片对食管恶性肿瘤的诊断准确性（94.12％）显着高于刷涂和挤压涂片（89.71％），内镜活检的诊断准确性为88.24％。联合刷牙和活检的诊断准确性为100％;触摸涂片结合活检的比例为97.06％。相比之下，仅刷牙对胃恶性肿瘤的诊断准确性为75％，明显低于触摸涂片（87.5％）和内窥镜活检（87.5％）。挤压涂片的诊断产率为81.25％。触摸涂片和活组织检查相结合的诊断率为100％。联合刷牙和活检的比率为93.75％。结论：细胞组织学技术的组合导致胃食管恶性肿瘤的诊断率在统计学上显着提高，因此细胞学技术可作为活检组织学的辅助手段以提高诊断效率。

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《Acta Cytologica: The Journal of Clinical Cytology and Cytopathology》 |2008年第1期|共6页
作者
Batra M; Handa U; Mohan H; Sachdev A;
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正文语种 eng
中图分类细胞生物学;病理学;
关键词
Malignant Neoplasms; biopsy characteristics; brushin; Tactual Perception;

机译：恶性肿瘤;活检特性;毛刷;触觉;

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机译：细胞组织学技术在胃食管恶性肿瘤诊断中的比较。
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Comparison of cytohistologic techniques in diagnosis of gastroesophageal malignancy.

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