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首页> 外文期刊>Biomaterials Science >A femtosecond Bessel laser for preparing a nontoxic slippery liquid-infused porous surface (SLIPS) for improving the hemocompatibility of NiTi alloys
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A femtosecond Bessel laser for preparing a nontoxic slippery liquid-infused porous surface (SLIPS) for improving the hemocompatibility of NiTi alloys

机译：用于制备无毒滑湿液体注入多孔表面（Slips）的飞秒贝塞尔激光，用于提高Niti合金的血液相位性

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摘要

A slippery liquid-infused porous surface (SLIPS) is able to improve the hemocompatibility of implantable medical materials, which have saved countless lives. However, the preparation of a SLIPS on an implantable metal substrate (especially NiTi alloys) is still a substantial challenge because of the great difficulty of forming abundant porous microstructures on hard metals. In this paper, a novel strategy to prepare a SLIPS on a NiTi alloy substrate is reported. We used the laser pulse train of a femtosecond Bessel laser rather than the common Gaussian beam to directly create deep porous microstructures on the surface of the implantable NiTi alloy. Based on the laser-induced porous microstructure, the SLIPS was obtained by lowering the surface energy and infusing the lubricant liquid into the pores. The as-prepared SLIPS very effectively repelled water and blood. The hemocompatibility of the NiTi alloy was greatly improved after the formation of the SLIPS by the femtosecond Bessel laser processing. It was demonstrated that the SLIPS gives the NiTi alloy a remarkable anticoagulation property, very low hemolysis rate, and antibacterial property. We believe that the laser-induced SLIPS will accelerate the broad application of metal implants in the medical field in a healthier and safer way.
机译：光滑的液体注入多孔表面（SLIPS）能够改善植入医疗材料的血液相位力，这些材料挽救了无数寿命。然而，在可植入的金属基材（特别是Nity合金）上的制备仍然是一个大量挑战，因为在硬质金属上形成丰富的多孔微观结构很难。本文报道了一种在NITI合金基质上制备滑动的新策略。我们使用了飞秒贝塞尔激光的激光脉冲序列，而不是共同的高斯光束，直接在可植入的Niti合金的表面上直接产生深孔微结构。基于激光诱导的多孔微观结构，通过降低表面能并将润滑剂液体注入孔中来获得滑动。制备的单击非常有效地排斥水和血液。通过Femtosecond Bessel激光加工形成滑动后，NITI合金的血液相容性大大提高。结果表明，滑动使NITI合金具有显着的抗凝血性能，非常低的溶血率和抗菌性。我们认为激光诱导的滑石将以更健康和更​​安全的方式加速金属植入物的广泛应用。

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  • 来源
    《Biomaterials Science》 |2020年第23期|共10页
  • 作者

    Cheng Yang; Yang Qing; Lu Yu; Yong Jiale; Fang Yao; Hou Xun; Chen Feng;

  • 作者单位

    Xi An Jiao Tong Univ Sch Mech Engn Xian 710049 Peoples R China;

    Xi An Jiao Tong Univ Sch Mech Engn Xian 710049 Peoples R China;

    Xi An Jiao Tong Univ Int Joint Res Lab Micro Nano Mfg &

    Measurement Te Xian 710049 Peoples R China;

    Xi An Jiao Tong Univ Int Joint Res Lab Micro Nano Mfg &

    Measurement Te Xian 710049 Peoples R China;

    Xi An Jiao Tong Univ Int Joint Res Lab Micro Nano Mfg &

    Measurement Te Xian 710049 Peoples R China;

    Xi An Jiao Tong Univ Sch Elect Sci &

    Engn State Key Lab Mfg Syst Engn Xian 710049 Peoples R China;

    Xi An Jiao Tong Univ Int Joint Res Lab Micro Nano Mfg &

    Measurement Te Xian 710049 Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 分子生物学;
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