Recombinant MVA generating excess early double-stranded RNA transiently activates PKR and triggers enhanced innate immune responses

Wolferstaetter Michael; Schweneker Marc; Spaeth Michaela; Lukassen Susanne; Klingenberg Marieken; Brinkmann Kay; Wielert Ursula; Lauterbach Henning; Hochrein Hubertus; Chaplin Paul; Suter Mark; Hausmann Juergen

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Recombinant MVA generating excess early double-stranded RNA transiently activates PKR and triggers enhanced innate immune responses

机译：产生过量早期双链RNA的重组MVA瞬时激活PKR并触发增强的先天免疫反应

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《Cytokine》 |2015年第1期|共2页
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Wolferstaetter Michael; Schweneker Marc; Spaeth Michaela; Lukassen Susanne; Klingenberg Marieken; Brinkmann Kay; Wielert Ursula; Lauterbach Henning; Hochrein Hubertus; Chaplin Paul; Suter Mark; Hausmann Juergen;
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正文语种 eng
中图分类细胞生物学;
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1. Recombinant MVA generating excess early double-stranded RNA transiently activates PKR and triggers enhanced innate immune responses [J] . Wolferstaetter Michael, Schweneker Marc, Spaeth Michaela, Cytokine . 2015,第1期

机译：产生过量早期双链RNA的重组MVA瞬时激活PKR并触发增强的先天免疫反应
2. Deletion of A44L , A46R and C12L Vaccinia Virus Genes from the MVA Genome Improved the Vector Immunogenicity by Modifying the Innate Immune Response Generating Enhanced and Optimized Specific T-Cell Responses [J] . María Pía Holgado, Juliana Falivene, Cynthia Maeto, Viruses . 2016,第5期

机译：从MVA基因组中删除A44L，A46R和C12L痘苗病毒基因，通过修饰先天免疫应答，产生增强和优化的特定T细胞应答，从而改善了载体的免疫原性。
3. Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA–triggered innate immune responses [J] . Charles E. Samuel The Journal of biological chemistry . 2019,第5期

机译：腺苷脱氨酶作用于RNA（ADAR1），是双链RNA触发的先天免疫应答的抑制剂
4. MOLECULAR INSIGHTS INTO PKR ACTIVATION BY VIRAL DOUBLE-STRANDED RNA [C] . SEAN A. MCKENNA, DARRIN A. LINDHOUT, COLIN ECHEVERRIA AITKEN, NATO Advanced Study Institute on Structure and Biophysics--New Technologies for Current Challenges in Biology and Beyond . 2007

机译：病毒双链RNA的PKR活化分子见解
5. Roles for the double-stranded RNA-dependent protein kinase PKR in apoptosis and innate immunity to viral infection. [D] . Balachandran, Siddharth. 2001

机译：双链RNA依赖性蛋白激酶PKR在凋亡和对病毒感染的固有免疫中的作用。
6. Recombinant Modified Vaccinia Virus Ankara Generating Excess Early Double-Stranded RNA Transiently Activates Protein Kinase R and Triggers Enhanced Innate Immune Responses [O] . Michael Wolferstätter, Marc Schweneker, Michaela Späth, 2014

机译：重组修饰的痘苗病毒安卡拉产生过量的早期双链RNA瞬时激活蛋白激酶R并触发增强的先天免疫反应。
7. Recombinant Modified Vaccinia Virus Ankara Generating Excess Early Double-Stranded RNA Transiently Activates Protein Kinase R and Triggers Enhanced Innate Immune Responses [O] . Michael Wolferstätter, Marc Schweneker, Michaela Späth, 2014

机译：重组改性痘苗病毒Ankara产生过量的早期双链RNA，瞬时激活蛋白激酶R并触发增强先天免疫应答

Recombinant MVA generating excess early double-stranded RNA transiently activates PKR and triggers enhanced innate immune responses

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