SPP1, analyzed by bioinformatics methods, promotes the metastasis in colorectal cancer by activating EMT pathway

Xu Chunjie; Sun Longci; Jiang Chunhui; Zhou Hong; Gu Lei; Liu Ye; Xu Qing

首页> 外文期刊>Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie >SPP1, analyzed by bioinformatics methods, promotes the metastasis in colorectal cancer by activating EMT pathway

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SPP1, analyzed by bioinformatics methods, promotes the metastasis in colorectal cancer by activating EMT pathway

机译：通过生物信息学方法分析SPP1，通过激活EMT途径促进结肠直肠癌中的转移

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Objective: Tumor metastasis is still a great challenge for the prognosis of colorectal cancer (CRC). Although secreted phosphoprotein 1 (SPP1) over-expression is confirmed to associate with invasion, metastasis of CRC, the underlying mechanism by which modulates the CRC metastasis is still not fully explained.

机译：目的：肿瘤转移仍为结肠直肠癌（CRC）预后的巨大挑战。尽管分泌的磷蛋白1（SPP1）过表达被证实与侵袭相关，CRC转移，其仍未完全解释调节CRC转移的潜在机制。

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来源
《Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie》 |2017年第2017期|共11页
作者
Xu Chunjie; Sun Longci; Jiang Chunhui; Zhou Hong; Gu Lei; Liu Ye; Xu Qing;
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作者单位

Shanghai Jiao Tong Univ Sch Med Renji Hosp Dept Gastrointestinal Surg 160 Pujian Rd Shanghai;

Shanghai Jiao Tong Univ Sch Med Renji Hosp Dept Gastrointestinal Surg 160 Pujian Rd Shanghai;

Shanghai Jiao Tong Univ Sch Med Renji Hosp Dept Gastrointestinal Surg 160 Pujian Rd Shanghai;

Shanghai Jiao Tong Univ Sch Med Renji Hosp Dept Gastrointestinal Surg 160 Pujian Rd Shanghai;

Shanghai Jiao Tong Univ Sch Med Renji Hosp Dept Gastrointestinal Surg 160 Pujian Rd Shanghai;

Shanghai Jiao Tong Univ Sch Med Renji Hosp Dept Gastrointestinal Surg 160 Pujian Rd Shanghai;

Shanghai Jiao Tong Univ Sch Med Renji Hosp Dept Gastrointestinal Surg 160 Pujian Rd Shanghai;

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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
Secreted phosphoprotein 1; Colorectal cancer; Metastasis; Epithelial-mesenchymal-transition; Bioinformatics;

机译：分泌的磷蛋白1;结直肠癌;转移;上皮 - 间充质转换;生物信息学;

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专利

1. SPP1, analyzed by bioinformatics methods, promotes the metastasis in colorectal cancer by activating EMT pathway [J] . Xu Chunjie, Sun Longci, Jiang Chunhui, Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2017,第期

机译：通过生物信息学方法分析SPP1，通过激活EMT途径促进结肠直肠癌中的转移
2. RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer [J] . Qingyuan Li, Qiuhua Lai, Chengcheng He, Journal of experimental & clinical cancer research : . 2019,第1期

机译：RUNX1通过激活Wnt /β-catenin信号通路和EMT促进结直肠癌的肿瘤转移
3. Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer. [J] . Yoo YA, Kang MH, Lee HJ, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2011,第22期

机译：声波刺猬通路通过激活Akt，EMT和MMP-9途径促进胃癌的转移和淋巴管生成。
4. A Pathway-Based Classification Method That Can Improve Microarray-Based Colorectal Cancer Diagnosis [C] . Hong-Qiang Wang, Xin-Ping Xie, Chun-Hou Zheng ICIC 2011;International conference on intelligent computing . 2012

机译：一种基于途径的分类方法，可以改善基于微阵列的结直肠癌的诊断
5. Investigation of Ras dependent signaling pathways in promoting experimental prostate cancer metastasis. [D] . Tillman, Heather Wood Sheppard. 2016

机译：Ras依赖性信号通路在促进实验性前列腺癌转移中的研究。
6. Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer [O] . Dingsheng Liu, Hong Zhang, Mingming Cui, 2020

机译：通过激活CTNND1介导的β-catenin途径和emt在结肠直肠癌中促进肿瘤生长和转移促进肿瘤生长和转移
7. SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway [O] . Lei Lv, Qiyi Yi, Ying Yan, 2021

机译：SPNS2下调诱导EMT并通过激活AKT信号通路促进结肠直肠癌转移

SPP1, analyzed by bioinformatics methods, promotes the metastasis in colorectal cancer by activating EMT pathway

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