Cytokine production by in vitro processed and unprocessed haematopoietic cells.

Bi S; Gao X; Devemy E; Chopra H; Venugopal P; Raza A; Preisler HD

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Cytokine production by in vitro processed and unprocessed haematopoietic cells.

机译：体外加工和未加工的造血细胞产生细胞因子。

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The studies described here demonstrate that in vitro processing of cells before extraction of RNA has a major effect on the number and type of cytokine transcripts present within MDS and leukemia cells. Transcripts for GM-CSF, a cytokine whose production by leukemia cells is believed to play an important role in the pathogenesis of leukemia, was not detectable in 12/13 unprocessed AML specimens, in 12/12 MDS specimens, or in 7/7 CML specimens but once detected in many specimens after processing. These data strongly suggest that leukemia cell production of GMCSF rarely occurs in vivo. Copyright 2000 Academic Press.

机译：此处描述的研究表明，提取RNA之前对细胞进行体外处理对MDS和白血病细胞内存在的细胞因子转录本的数量和类型有重大影响。在12/13未经处理的AML标本，12/12 MDS标本或7/7 CML标本中均未检测到GM-CSF的转录本，GM-CSF是一种由白血病细胞产生的细胞因子，被认为在白血病的发病机理中具有重要作用。标本，但经过处理后在许多标本中被检测到。这些数据强烈暗示GMCSF的白血病细胞产生很少在体内发生。版权所有2000学术出版社。

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《Cytokine》 |2000年第7期|共5页
作者
Bi S; Gao X; Devemy E; Chopra H; Venugopal P; Raza A; Preisler HD;
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正文语种 eng
中图分类细胞生物学;
关键词
Bone Marrow Cells; Cytokines; 骨髓细胞; 细胞活素类;

机译：Bone Marrow Cells;Cytokines;骨髓细胞;细胞活素类;

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1. Cytokine production by in vitro processed and unprocessed haematopoietic cells. [J] . Bi S, Gao X, Devemy E, Cytokine . 2000,第7期

机译：体外加工和未加工的造血细胞产生细胞因子。
2. Effects of interleukin-4 on the in-vitro production of cytokines by human endometrial stromal cells. [J] . Nasu K, Sugano T, Fujisawa K, Molecular human reproduction. . 2001,第3期

机译：白细胞介素4对人子宫内膜基质细胞体外产生细胞因子的影响。
3. Opposing effects of sodium salicylate and haematopoietic cytokines IL-3, IL-5 and GM-CSF on mitogen-activated protein kinases and apoptosis of EoL-1 cells. [J] . Wong CK, Zhang JP, Lam CW, Immunological Investigations: A Journal of Molecular and Cellular Immunology . 1999,第5a6期

机译：水杨酸钠和造血细胞因子IL-3，IL-5和GM-CSF对有丝分裂原激活的蛋白激酶和EoL-1细胞凋亡的相反作用。
4. Use of Unprocessed Rice Husk Ash and Pulverized Fuel Ash in the Production of Self-Compacting Concrete [C] . Gritsada Sua-iam, Natt Makul International Conference on Agricultural and Natural Resources Engineering . 2014

机译：使用未处理的稻壳灰和粉碎的燃料灰在自压制混凝土的生产中
5. Effects of pro-inflammatory cytokines on in vitro measures of gene expression, protein expression, and process extension in primary hippocampal neurons. [D] . McLinden, Kristina Ashley. 2011

机译：促炎性细胞因子对原代海马神经元基因表达，蛋白质表达和过程扩展的体外测量的影响。
6. Stability of cytokines chemokines and soluble activation markers in unprocessed blood stored under different conditions [O] . Najib Aziz, Roger Detels, Joshua J. Quint, -1

机译：在不同条件下储存的未加工血液中细胞因子趋化因子和可溶性激活标记物的稳定性
7. Stability of cytokines, chemokines and soluble activation markers in unprocessed blood stored under different conditions [O] . Najib Aziz, Roger Detels, Joshua J. Quint, 2016

机译：在不同条件下储存未加工血液中细胞因子，趋化因子和可溶性活化标志物的稳定性

Cytokine production by in vitro processed and unprocessed haematopoietic cells.

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