• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BJU international >Comparison of accuracy of 14-, 18- and 20-G needles in ex-vivo renal mass biopsy: a prospective, blinded study.
【24h】

Comparison of accuracy of 14-, 18- and 20-G needles in ex-vivo renal mass biopsy: a prospective, blinded study.

机译：在体内肾肿块活检中14-，18〜20g和20g针的精度比较：令人盲化的研究。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To prospectively determine the accuracy of 14-, 18- and 20-G core needle biopsies to render the appropriate histological diagnosis of solid, enhancing renal masses, using a controlled, ex-vivo biopsy technique. PATIENTS AND METHODS: From March 2007 to September 2007, 31 patients undergoing partial or radical nephrectomy were randomly selected for biopsy. After extirpative surgery, three ex-vivo biopsies were taken from each lesion with 14-, 18- and 20-G biopsy needles. One experienced genitourinary pathologist, unaware of patient identifiers and final pathology results, determined the biopsy histology and tumour grade, based on standard haematoxylin and eosin (H&E) techniques and immunohistochemistry. RESULTS: The final pathological evaluation classified 21 masses (68%) as clear cell renal cell carcinoma (RCC), three (10%) as papillary RCC, three (10%) as chromophobe RCC, three (10%) as oncocytoma and one (3%) as a benign lymphoid infiltrate. The biopsy histology correlated with the final pathology in 29/31 cases (94%) with the 14-G, 30/31 cases (97%) with the 18-G and 25/31 cases (81%) with the 20-G needles. In two cases chromophobe RCC was misdiagnosed with oncocytoma, and vice versa. CONCLUSION: In this study a minimum of an 18-G biopsy needle was the most accurate in determining the histological diagnosis. Clear cell and papillary RCCs were accurately diagnosed on biopsy using an 18-G, whereas oncocytoma and chromophobe RCC were difficult to differentiate using standard H&E techniques and immunohistochemistry.
机译：目的：潜在确定14-，18〜20g核心针活检的准确性，以使使用受控的ex-体内活组织检查技术使固体，增强肾气块的适当组织学诊断。患者和方法：从2007年3月到2007年9月，随机选择31例接受部分或根治性肾切除术的患者进行活组织检查。在脱悬浮后，从每个病变中取出三个前体内活组织检查，其中14-14,18-18-10g活组织检查针。一种经验丰富的泌尿病病理学家，不知道患者标识符和最终病理结果，确定基于标准血红素和曙红（H＆E）技术和免疫组化的活组织检查组织学和肿瘤等级。结果：最终病理评价分类为21质量（68％）作为透明细胞肾细胞癌（RCC），三（10％），为乳头状RCC，三（10％）作为发色体RCC，三（10％）为一生瘤和一个（3％）作为良性淋巴渗透。活检组织学与29/31例（94％）的最终病理学相关，其中14-g，30/31例（97％），18-g和25/31例（81％），20g针。在两种情况下，发色团RCC误诊为具有癌细胞瘤的误诊，反之亦然。结论：在这项研究中，最少的18g活检针是最准确的决定组织学诊断。使用18g的活组织检查精确地诊断透明细胞和乳头状rCC，而群体细胞瘤和发球率难以使用标准的H＆E技术和免疫组化来区分。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号