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Inter-arm difference of systolic blood pressure measured by automated double-cuff device is associated with arterial stiffness in patients with hypertension

机译:通过自动双袖带装置测量的收缩压的互臂差异与高血压患者的动脉僵硬有关

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摘要

Purpose Inter-arm differences of SBP ≧5 mmHg have been associated with all-cause and cardiovascular mortalities in hypertensive subjects. Inter-arm differences of SBP appears to be mediated by arterial stiffness. We hypothesized inter-arm differences of SBP ≧5 mmHg may be related to higher pulse pressure/stroke volume index, a surrogate marker of arterial stiffness. Materials and methods To obtain inter-arm differences of SBP (the absolute difference of right and left arm) and ankle-brachial index, bilateral blood pressures were measured simultaneously at the four limbs using an automated oscillometric device in patients with treated hypertension (n = 234) and in normotensive subjects (n = 40). Pulse pressure was calculated as SBP–DBP. Stroke volume was obtained by time-velocity integral method using echocardiography. Left ventricular mass and relative wall thickness were calculated by the conventional methods. Results All hypertensive patients were medically treated and had average blood pressure levels of 135/85 mmHg. Inter-arm differences of SBP ≧5 mmHg was detected in 26.5% of hypertensive patients. Hypertensive patients with inter-arm differences of SBP ≧5 mmHg had higher pulse pressure/stroke volume index, lower ankle-brachial index, higher BMI, and higher relative wall thickness, higher prevalence of female than those with inter-arm differences of SBP <5 mmHg. Multiple linear regression analysis confirmed inter-arm differences of SBP ≧5 mmHg was associated with higher pulse pressure/stroke volume index, higher relative wall thickness, and lower ankle-brachial index. Conclusion Inter-arm difference of SBP measured by automated double-cuff device was related to large artery stiffness in patients with hypertension.
机译:目的,SBP≧5mmHg的臂间差异已经与高血压患者的全因和心血管凡人有关。 SBP的臂间差异似乎被动脉刚度介导。我们假设SBP≧5mmHg的臂间差异可能与较高的脉冲压力/行程体积指数相关,动脉刚度的替代标记。获得臂间差异的材料和方法(右侧和左臂的绝对差)和踝臂指数,使用治疗高血压患者的自动示波器装置在四肢同时测量双侧血压(n = 234)和正常血压(n = 40)。脉冲压力计算为SBP-DBP。通过使用超声心动图的时间速度积分法得到行程体积。通过常规方法计算左心室质量和相对壁厚。结果所有高血压患者在医学上进行治疗,平均血压水平为135 / 85mmHg。在26.5%的高血压患者中检测到SBP≧5mmHg的臂间差异。高血压患者的臂间差异的SBP≧5mmHg具有较高的脉冲压力/行程体积指数,较低的脚踝 - 臂指数,更高的BMI和更高的相对壁厚,女性流行高于SBP的臂间差异的女性流行率更高< 5 mmhg。多元线性回归分析证实了SBP≧5mmHg的臂间差异与较高的脉冲压力/行程容积指数,更高的相对壁厚和较低的踝臂指数相关。结论自动双袖带装置测量的SBP的间臂差异与高血压患者的大动脉僵硬。

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  • 来源
    《Blood Pressure Monitoring》 |2020年第1期|共8页
  • 作者单位

    Department of Cardiology Aichi Sannomaru Clinic;

    Department of Cardiology Aichi Sannomaru Clinic;

    Department of Endocrinology Unit of Cardiovascular Research Research Institute of Environmental;

    Department of Endocrinology Unit of Cardiovascular Research Research Institute of Environmental;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 内科学;
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