首页> 外文期刊>The journal of clinical hypertension. >Relationship Between Inter-Arm Difference in Systolic Blood Pressure and Arterial Stiffness in Community-Dwelling Older Adults
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Relationship Between Inter-Arm Difference in Systolic Blood Pressure and Arterial Stiffness in Community-Dwelling Older Adults

机译:居住在社区的老年人的臂间收缩压差异与动脉僵硬度之间的关系

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A significant inter-arm difference in systolic blood pressure (IADSBP) has recently been associated with worse cardiovascular outcomes. The authors hypothesized that part of this association is mediated by arterial stiffness, and examined the relationship between significant IADSBP and carotid-femoral pulse wave velocity (CF-PWV) in a sample from the Baltimore Longitudinal Study of Aging. Of 1045 participants, 50 (4.8%) had an IADSBP ≥10 mm Hg at baseline, and 629 had completed data from ≥2 visits (for a total of 1704 visits during 8 years). CF-PWV was significantly higher in patients with an IADSBP ≥10 mm Hg (7.3±1.9 vs 8.2±2, P=.002). Compared with others, patients with IADSBP ≥10 mm Hg also had higher body mass index, waist circumference, and triglycerides; higher prevalence of diabetes; and lower high-density lipoprotein (HDL) cholesterol (P<.001 for all). A significant association with IADSBP ≥10 mm Hg was observed for CF-PWV in both cross-sectional (odds ratio [OR], 1.19; 95% confidence interval [CI], 1.06-1.87; P=.01) and longitudinal (OR, 1.15; 95% CI, 1.03-1.29; P=.01) multivariate analyses. Female sex, Caucasian race, high body mass index (plus diabetes and low HDL cholesterol only cross-sectionally) were other independent correlates of IADSBP ≥10 mm Hg. Significant IADSBP is associated with increased arterial stiffness in community-dwelling older adults.
机译:臂间收缩压的显着差异(IADSBP)最近与心血管疾病恶化相关。作者假设这种关联的一部分是由动脉僵硬度介导的,并研究了巴尔的摩纵向衰老研究的样本中明显的IADSBP与颈动脉股动脉脉搏波速度(CF-PWV)之间的关系。在1045名参与者中,有50名(4.8%)的IADSBP在基线时≥10 mm Hg,有629名已完成≥2次就诊的数据(8年中总共1704次就诊)。 IADSBP≥10 mm Hg的患者CF-PWV显着更高(7.3±1.9 vs 8.2±2,P = .002)与其他患者相比,IADSBP≥10 mm Hg的患者的体重指数,腰围和甘油三酸酯也更高;糖尿病患病率更高;和较低的高密度脂蛋白(HDL)胆固醇(所有P均<0.001)。 CF-PWV的横截面(奇数比[OR]为1.19; 95%置信区间[CI]为1.06-1.87; P = .01)和纵向(OR)均与IADSBP≥10mm Hg显着相关。 ,1.15; 95%CI,1.03-1.29; P = .01)多元分析。 IADSBP≥10mm Hg的其他独立相关因素包括女性,白种人,高体重指数(加上糖尿病和低水平的HDL胆固醇)。 IADSBP显着增加与社区居民老年人的动脉僵硬度相关。

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