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首页> 外文期刊>Brain, Behavior, and Immunity >Feeling needed: Effects of a randomized generativity intervention on well-being and inflammation in older women
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Feeling needed: Effects of a randomized generativity intervention on well-being and inflammation in older women

机译：所需的感觉：随机发电度干预对老年女性福祉和炎症的影响

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Generativity, or concern for and contribution to the well-being of younger generations, plays an important role in successful aging. The purpose of this study was to develop a novel, writing-based intervention to increase feelings of generativity and test the effect of this intervention on well-being and inflammation in a sample of older women. Participants in this study (n = 73; mean age = 70.9 years, range 60-86 years) were randomly assigned to a 6-week generativity writing condition (writing about life experiences and sharing advice with others) or a control writing condition (neutral, descriptive writing). Self-reported measures of social well-being, mental health, and physical health, as well as objective measures of systemic and cellular levels of inflammation (plasma pro-inflammatory cytokines interleukin-6 and tumor necrosis factor-alpha; genome-wide RNA transcriptional profiling), were assessed pre- and post-intervention. The generativity intervention led to significant improvements across multiple domains, including increases in participation in social activities, decreases in psychological distress, more positive expectations regarding aging in the physical health domain, and decreases in pro-inflammatory gene expression. Thus, this study provides preliminary evidence for the ability of a novel, low-cost, low-effort intervention to favorably impact inflammation and well-being in older women
机译：发电性，或对年轻世代的福祉的担忧和贡献，在成功的老龄化中起着重要作用。本研究的目的是制定一种新颖的写作的干预，以增加发电情绪并测试这种干预对老年妇女样本中福祉和炎症的影响。本研究中的参与者（n = 73;平均年龄= 70.9岁，范围60-86岁）被随机分配到6周的发电性写作条件（关于生命经验和与他人分享建议）或控制写作条件（中性，描述性写作）。自我报告的社会福祉，心理健康和身体健康的措施，以及炎症的系统性和细胞水平的客观措施（血浆促炎细胞因子白细胞介素-6和肿瘤坏死因子-α;基因组RNA转录分析），被评估预先和干预后。发电性干预导致多个领域的显着改善，包括参与社会活动的增加，心理困扰降低，对身体健康域中的老龄化的更积极的预期，并降低促炎基因表达。因此，本研究为新颖，低成本，低努力干预的能力提供了初步证据，以对老年妇女有利地影响炎症和福祉

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