Association of tumor necrosis factor-alpha and interferon gamma gene polymorphisms and their plasma levels in leprosy, HIV and other peripheral neuropathies

Sykam Aparna; Gutlapalli V. R.; Tenali Sandeep P.; Meena A. K.; Chandran Priscilla; Pratap D. V. S.; Suneetha Sujai; Suneetha Lavanya M.

首页> 外文期刊>Cytokine >Association of tumor necrosis factor-alpha and interferon gamma gene polymorphisms and their plasma levels in leprosy, HIV and other peripheral neuropathies

【24h】

Association of tumor necrosis factor-alpha and interferon gamma gene polymorphisms and their plasma levels in leprosy, HIV and other peripheral neuropathies

机译：麻风病，HIV和其他周围神经病中肿瘤坏死因子-α和干扰素γ基因多态性与血浆水平的关联

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Objective: Mycobacterium leprae and Human Immunodeficiency Virus (HIV) are causative agents known to be involved in nerve damage in leprosy and HIV-peripheral neuropathy (HIV-PN) respectively. Among other peripheral neuropathies the most common is diabetic neuropathy, which is metabolically induced. The proinflammatory cytokines TNF-alpha and IFN-gamma have been implicated in the pathogenesis of peripheral neuropathy. The association between the plasma levels of these cytokines and their single nucleotide polymorphisms (SNPs) were investigated in leprosy neuropathy (LN), HIV-PN and other peripheral neuropathies (OPN).

机译：目的：麻风分枝杆菌和人类免疫缺陷病毒（HIV）分别是引起麻风病和HIV周围神经病（HIV-PN）神经损伤的病原体。在其他周围神经病中，最常见的是糖尿病性神经病，它是由代谢引起的。促炎细胞因子TNF-α和IFN-γ已牵涉到周围神经病的发病机理中。在麻风性神经病（LN），HIV-PN和其他周围神经病（OPN）中研究了这些细胞因子的血浆水平与其单核苷酸多态性（SNP）之间的关联。

著录项

来源
《Cytokine》 |2015年第2期|共7页
作者
Sykam Aparna; Gutlapalli V. R.; Tenali Sandeep P.; Meena A. K.; Chandran Priscilla; Pratap D. V. S.; Suneetha Sujai; Suneetha Lavanya M.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类细胞生物学;
关键词
Leprosy; HIV-peripheral neuropathy; TNF-alpha; IFN-gamma; Single nucleotide polymorphisms;

机译：麻风病;HIV周围神经病;TNF-α;IFN-γ;单核苷酸多态性;

相似文献

外文文献
中文文献
专利

1. Association of tumor necrosis factor-alpha and interferon gamma gene polymorphisms and their plasma levels in leprosy, HIV and other peripheral neuropathies [J] . Sykam Aparna, Gutlapalli V. R., Tenali Sandeep P., Cytokine . 2015,第2期

机译：麻风病，HIV和其他周围神经病中肿瘤坏死因子-α和干扰素γ基因多态性与血浆水平的关联
2. Associations between cytotoxic T lymphocyte-associated antigen-4 polymorphisms and serum tumor necrosis factor-alpha and interferon-gamma levels in patients with chronic hepatitis B virus infection. [J] . Han Q, Duan S, Zhang G, Inflammation research: Official journal of the European Histamine Research Society . 2011,第11期

机译：慢性乙型肝炎病毒感染患者的细胞毒性T淋巴细胞相关抗原4多态性与血清肿瘤坏死因子-α和干扰素-γ水平之间的关联。
3. Association of interferon-gamma, interleukin-10, and tumor necrosis factor-alpha gene polymorphisms with occurrence and severity of Eales' disease. [J] . Sen A, Paine SK, Chowdhury IH, Investigative ophthalmology & visual science . 2011,第1期

机译：干扰素-γ，白介素-10和肿瘤坏死因子-α基因多态性与Eales病的发生和严重程度相关。
4. Tumor Necrosis Factor-alpha (TNF-alpha) Gene -238 Single Nucleotide Polymorphism (SNP) Is Associated with Low TNF-a Production from Peripheral Blood Mononuclear Cells (PBMCs) in Japanese [C] . K. Shuno, M. Aoyama, S. Fudo, Conference on Shock . 2008

机译：肿瘤坏死因子-α（TNF-α）基因-238单核苷酸多态性（SNP）与日本外周血单核细胞（PBMC）的低TNF-A生产相关
5. New insights into tumor necrosis factor-alpha in cancer: Distinct isoforms exert opposing effects on tumor associated myeloid cells and tumorigenesis. [D] . Ardestani, Shidrokh. 2013

机译：对癌症中肿瘤坏死因子-α的新见解：不同的同工型对肿瘤相关的髓样细胞和肿瘤发生具有相反的作用。
6. Cytokine Gene Polymorphisms in Childhood Dilated Cardiomyopathy: Interferon- gamma Tumor Necrosis Factor-alpha and Transforming Growth Factor - beta 1 Genes Are Associated with the Disease in Turkish Patients [O] . Sibel Oguzkan Balci, Nilgun Col-Araz, Osman Baspinar, 2013

机译：儿童扩张型心肌病中的细胞因子基因多态性：土耳其患者该疾病与干扰素肿瘤坏死因子-α和转化生长因子-β1基因相关。
7. Tumor necrosis factor-alpha and interferon-gamma suppress the activation of human type I collagen gene expression by transforming growth factor-beta 1. Evidence for two distinct mechanisms of inhibition at the transcriptional and posttranscriptional levels. [O] . Kähäri, V M, Chen, Y Q, Su, M W, 1990

机译：肿瘤坏死因子-α和干扰素-γ通过转化生长因子-β1抑制人类I型胶原基因表达的激活。证据表明在转录和转录后水平存在两种不同的抑制机制。

Association of tumor necrosis factor-alpha and interferon gamma gene polymorphisms and their plasma levels in leprosy, HIV and other peripheral neuropathies

摘要

著录项

相似文献

相关主题

期刊订阅