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An update on minding the gap in cancer

机译：关于癌症差距的更新

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摘要

Abstract This article is a report of the “International Colloquium on Gap junctions: 50Years of Impact on Cancer” that was held 8–9 September 2016, at the Amphitheater “P?le Biologie Santé” of the University of Poitiers (Poitiers, France). The colloquium was organized by M Mesnil (Université de Poitiers, Poitiers, France) and C Naus (University of British Columbia, Vancouver, Canada) to celebrate the 50th anniversary of the seminal work published in 1966 by Loewenstein and Kanno [Intercellular communication and the control of tissue growth: lack of communication between cancer cells, Nature, 116 (1966) 1248–1249] which initiated studies on the involvement of gap junctions in carcinogenesis. During the colloquium, 15 participants presented reviews or research updates in the field which are summarized below. Highlights ? This article is a report of the “International Colloquium on Gap junctions: 50Years of Impact on Cancer” that was held 8–9 September 2016. ? The purpose was to celebrate the 50th anniversary of the seminal work published in 1966 by Loewenstein and Kanno [Intercellular communication and the control of tissue growth: lack of communication between cancer cells, Nature, 116 (1966) 1248–1249] which initiated studies on the involvement of gap junctions in carcinogenesis. ? During the colloquium, 15 participants presented reviews or research updates in the field which are summarized in this review.
机译：摘要本文是2016年9月8日至9日举行的“差距交界处的国际集团群体国际博物情议程：50年对癌症的影响”的报告，该报告于2016年9月8日至9日举行的彩虹池（Poitiers，France）的圆形剧场“P？Le BiologieSanté” 。由M Mesnil（Universitédepoitiers，博伊特，法国）和C Naus（不列颠哥伦比亚省大学，加拿大大学）组织了斗篷，以庆祝1966年由Loewenstein和Kanno [细胞间通信和组织生长的控制：癌细胞，自然，116（1966）1248-1249之间的沟通缺乏关于致癌间隙连接的参与的研究。在会议期间，15名参与者在下面汇总的介绍或研究更新中提出了审查或研究更新。强调 ？本文是2016年9月8日至9日举行的“差距交界处的国际差距联盟委员会的国际集团：50年的影响”的报告。目的是通过Loewenstein和Kanno（细胞间通信和组织生长控制）庆祝1966年发布的开创性工作的50周年：癌细胞之间缺乏沟通，自然，116（1966）1248-1249启动的研究间隙结在致癌中的参与。还在会议期间，15名参与者在本次审查中展示了该领域的审查或研究更新。

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  • 来源
  • 作者

    Marc Mesnil; Trond Aasen; Jonathan Boucher; Amandine Chépied; Laurent Cronier; Norah Defamie; Petra Kameritsch; Dale W. Laird; Paul D. Lampe; Justin D. Lathia; Edward Leithe; Parmender P. Mehta; Arnaud Monvoisin; Kristin Pogoda; Wun-Chey Sin; Arantxa Tabernero; Hiroshi Yamasaki; Elizabeth S. Yeh; Maria Lucia Zaidan Dagli; Christian C. Naus;

  • 作者单位

    STIM Laboratory ERL 7368 CNRS – Faculté des Sciences Fondamentales et Appliquées Université de;

    Translational Molecular Pathology Vall d'Hebron Institute of Research (VHIR) Autonomous;

    STIM Laboratory ERL 7368 CNRS – Faculté des Sciences Fondamentales et Appliquées Université de;

    STIM Laboratory ERL 7368 CNRS – Faculté des Sciences Fondamentales et Appliquées Université de;

    STIM Laboratory ERL 7368 CNRS – Faculté des Sciences Fondamentales et Appliquées Université de;

    STIM Laboratory ERL 7368 CNRS – Faculté des Sciences Fondamentales et Appliquées Université de;

    Walter Brendel Centre of Experimental Medicine Ludwig-Maximilians-Universit?t München and Munich;

    Department of Anatomy and Cell Biology University of Western Ontario;

    Fred Hutchinson Cancer Research Center;

    Cleveland Clinic Lerner College of Medicine Case Western Reserve University;

    Department of Molecular Oncology Institute for Cancer Research Oslo University Hospital and;

    Department of Biochemistry and Molecular Biology University of Nebraska Medical Center;

    STIM Laboratory ERL 7368 CNRS – Faculté des Sciences Fondamentales et Appliquées Université de;

    Walter Brendel Centre of Experimental Medicine Ludwig-Maximilians-Universit?t München and Munich;

    Department of Cellular &

    Physiological Sciences Life Sciences Institute University of British;

    Departamento de Bioquímica y Biología Molecular Instituto de Neurociencias de Castilla y León;

    Kwansei Gakuin University;

    Department of Cell and Molecular Pharmacology and Experimental Therapeutics Medical University of;

    Laboratory of Experimental and Comparative Oncology School of Veterinary Medicine and Animal;

    Department of Cellular &

    Physiological Sciences Life Sciences Institute University of British;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物膜的结构和功能;
  • 关键词

    Cancer; Gap junction; Connexin; Tumor progression; Cell migration; Invasion;

    机译：癌症;间隙结;connexin;肿瘤进展;细胞迁移;入侵;

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