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首页> 外文期刊>Canadian pharmacists journal: CPJ = Revue des pharmaciens du Canada : RPC >Outcomes of Urinary Tract Infection Management by Pharmacists (RXOUTMAP): A study of pharmacist prescribing and care in patients with uncomplicated urinary tract infections in the community
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Outcomes of Urinary Tract Infection Management by Pharmacists (RXOUTMAP): A study of pharmacist prescribing and care in patients with uncomplicated urinary tract infections in the community

机译:药剂师(RXOUTMAP)的泌尿道感染管理结果:对社区简单尿路感染患者的药剂师处方和护理研究

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Background: Pharmacists have the authorization to prescribe medications for the treatment of uncomplicated urinary tract infections (UTI) in some provinces. However, there are limited data on the outcomes of this care by pharmacists. Our objective was to evaluate the effectiveness, safety and patient satisfaction with pharmacist prescribing and care in patients with uncomplicated UTI. Methods: We conducted a prospective registry trial in 39 community pharmacies in the Canadian province of New Brunswick. Adult patients were enrolled if they presented to the pharmacy with either symptoms of UTI with no current antibacterial treatment (Pharmacist-Initial Arm) or if they presented with a prescription for an antibacterial to treat UTI from another health care provider (Physician-Initial Arm). Pharmacists assessed patients and if they had complicating factors or red flags for systemic illness or pyelonephritis, they were excluded from the study. Pharmacists either prescribed antibacterial therapy, modified antibacterial therapy, provided education only or referred to physician, as appropriate.The primary outcome was clinical cure at 2 weeks and the secondary outcomes included adverse events and patient satisfaction. Results: A total of 750 patients were enrolled (87.4% in the Pharmacist-Initial Arm), average age was 40.9 (SD 16.0) years. Clinical cure was achieved in 88.9% of patients. Of those that did not have sustained symptom resolution, most (5.5% overall) had symptom recurrence after completion of therapy. Adverse events were reported by 7.2% of patients and 88.9% of those continued their medication. Most adverse events were gastrointestinal-related and transient. The patient satisfaction survey reflected very high levels of satisfaction for the care they received, as well as for trust and accessibility of the pharmacist. Conclusion: Pharmacist management of uncomplicated UTI is effective, safe, and patient satisfaction appears very high.
机译:背景:药剂师有授权在一些省份探索治疗外包尿路感染(UTI)的药物。但是,药剂师有关这项护理结果的数据有限。我们的目标是评估与未复杂的UTI患者的药剂师处方和护理的有效性,安全性和患者满意度。方法:我们在加拿大新不伦瑞克省的39个社区药房中进行了一项预期登记审判。如果它们与UTI的任何症状呈现给药房,则注册了成年人,没有目前的抗菌治疗(药剂师 - 初始手臂)或者如果它们呈现出抗菌的处方,以从另一种医疗保健提供者(医师 - 初始手臂)治疗UTI 。药剂师评估患者,如果它们具有复杂的因素或用于全身疾病或肾盂肾炎的红旗,它们被排除在研究之外。药品专家规定的抗菌疗法,改性抗菌治疗,仅适用于医生提供教育,尤其是临床治疗,次要结果包括不良事件和患者满意度。结果:共有750名患者(药剂师 - 初始手臂87.4%),平均年龄为40.9(SD 16.0)年。临床治疗方法是在88.9%的患者中实现。其中没有持续症状分辨率的人,大多数(总体总体5.5%)在完成后症状复发。报告了7.2%的患者的不良事件,88.9%的人继续进行药物。大多数不良事件是胃肠道相关和瞬态。患者满意度调查反映了他们收到的护理的满意度非常高,以及药剂师的信任和可访问性。结论:软化UTI的药剂师管理是有效的,安全,患者满意度看起来非常高。

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