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Interventions to Reduce Future Cancer Incidence from Diesel Engine Exhaust: What Might Work?

机译:干预措施,减少柴油发动机排气的未来癌症发病率:有什么可能的?

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摘要

Exposure to diesel engine exhaust (DEE) contributes appreciably to the burden of occupational cancer. This study aims to estimate the potential impact of a range of interventions on the future burden of cancer from occupational exposure to DEE in Australia. The future excess fraction method, a novel method based on the lifetime risk approach, was used to model changes in the future burden of cancer among the Australian working age population exposed to DEE at work in 2012 under various intervention strategies. The interventions modeled were based on the widely accepted hierarchy of control model. At baseline, 600 (0.4%) future bladder and 4,450 (0.6%) future lung cancer cases over the lifetime of the cohort were estimated to be attributable to occupational exposure to DEE in those exposed in 2012. Up to 2,000 of these cases were estimated to be avoidable through the use of various interventions. Exhaust hoses (engineering controls) were estimated to be particularly effective. This study provides an indication of which intervention strategies may be most useful in reducing the future burden of cancer associated with occupational DEE exposure. These results show the potential effect of changing current exposure, rather than focusing on past exposures, and thus provide relevant information for policy planning.
机译:暴露于柴油发动机排气(DEE),以促进职业癌症的负担。本研究旨在估算一系列干预措施对澳大利亚职业暴露的未来癌症负担的潜在影响。未来的超额分数法,一种基于寿命风险方法的新方法,用于在各种干预战略下在2012年在2012年在工作中接触到Dee的澳大利亚工作年龄的未来癌症负担的变化。建模的干预措施基于广泛接受的控制模型层次结构。在基线,600(0.4%)未来的膀胱和4,450%(0.6%)未来肺癌病例在队列的寿命上估计是由于2012年暴露的人职业暴露。估计最多2,000例通过使用各种干预措施来避免。估计尾气软管(工程控制)特别有效。本研究规定了哪些干预策略在减少与职业Dee暴露相关的未来癌症负担方面最有用。这些结果表明,改变电流曝光的潜在效果,而不是关注过去的曝光,从而为政策规划提供相关信息。

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  • 来源
    《Cancer prevention research.》 |2019年第1期|共8页
  • 作者单位

    Curtin Univ Sch Publ Hlth Bentley WA Australia;

    Curtin Univ Sch Publ Hlth Bentley WA Australia;

    Univ Sydney Sch Publ Hlth Sydney NSW Australia;

    Univ Western Australia Sch Global &

    Populat Hlth Nedlands WA Australia;

    Monash Univ Monash Ctr Occupat &

    Environm Hlth Sch Publ Hlth &

    Prevent Med Melbourne Vic;

    Monash Univ Monash Ctr Occupat &

    Environm Hlth Sch Publ Hlth &

    Prevent Med Melbourne Vic;

    Curtin Univ Sch Publ Hlth Bentley WA Australia;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 肿瘤学;
  • 关键词

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