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首页> 外文期刊>Cardiology >Torsion Mechanics as an Indicator of More Advanced Left Ventricular Systolic Dysfunction in Secondary Mitral Regurgitation in Patients with Dilated Cardiomyopathy: A 2D Speckle-Tracking Analysis
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Torsion Mechanics as an Indicator of More Advanced Left Ventricular Systolic Dysfunction in Secondary Mitral Regurgitation in Patients with Dilated Cardiomyopathy: A 2D Speckle-Tracking Analysis

机译:扭转力学作为扩张心肌病患者中次级二尖瓣再诊中更晚期左心室收缩功能障碍的指标:2D散斑跟踪分析

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Left ventricular (LV) twist serves as a compensatory mechanism in systolic dysfunction and its degree of reduction may reflect a more advanced stage of disease. Aim: The aim was to investigate twist alterations depending on the degree of functional mitral regurgitation (MR) by speckle-tracking echocardiography. Methods: Sixty-three patients with symptomatic dilated cardiomyopathy (DCM) were included. Patients were divided according to MR vena contracta width (VCW): group 1 with VCW Results: There were no differences in LV geometry and function between groups. Group 2 showed lower endocardial basal rotation (BR) (–2.04° ± 1.83° vs. –3.23° ± 1.83°, p = 0.012); epicardial BR (–1.54° ± 1.18° vs. –2.31° ± 1.22°, p = 0.015); endocardial torsion (0.41°/cm ± 0.36°/cm vs. 0.63°/cm ± 0.44°/cm, p = 0.033) and mid-level circumferential strain (CSmid) (–6.12% ± 2.64% vs. –7.75% ± 2.90%, p = 0.028), when compared with group 1. Multivariable linear regression analysis identified endocardial BR, torsion and CSmid, as the best predictors of larger VCW. In the ROC curve analysis, endocardial BR and CSmid values greater than or equal to –3.63° and –9.35%, respectively, can differentiate patients with severe MR. Conclusions: In DCM patients, torsional profile was more altered in severe MR. Endocardial BR, endocardial torsion, and CSmid, can be used as indicators of advanced structural wall architecture damage.
机译:左心室(LV)捻度用作收缩功能障碍的补偿机制,其减少程度可能反映出更先进的疾病阶段。目的:目的是根据斑点跟踪超声心动图的功能二尖瓣流反流度(MR)来研究扭曲变化。方法:包括六十三名症状性扩张心肌病(DCM)患者。患者根据vena接收宽度(VCW):第1组进行VCW结果:LV几何形状和组之间的功能差异。第2组表现出下内膜旋转(BR)(-2.04°±1.83°与-3.23°±1.83°,P = 0.012);心外膜(-1.54°±1.18°与-2.31°±1.22°,p = 0.015);内膜扭转(0.41°/ cm±0.36°/ cm vs.0.63°/ cm±0.44°/ cm,p = 0.033)和中级圆周菌株(CSMID)(-6.12%±2.64%vs. -7.75%± 2.90%,p = 0.028),与组比较1.多变量线性回归分析确定了内容性Br,扭转和csmid,作为较大Vcw的最佳预测因子。在ROC曲线分析中,外部内容BR和CSMID值分别大于或等于-3.63°和-9.35%,可以区分严重MR的患者。结论:在DCM患者中,严重MR的扭转型材更加改变。心内膜BR,心内膜扭转和CSMID,可用作先进的结构墙架构损坏的指标。

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