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Metabolic Adaptation Fuels Lymph Node Metastasis

机译:代谢适应燃料淋巴结转移

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摘要

Many cancers metastasize regionally through lymphatics before metastasizing systemically through blood vessels. However, metastasis through blood has been studied much more extensively than metastasis through lymph. Recently in Science, Lee et al. (2019) offered new insight into lymph node metastasis by showing that melanoma cells must undergo metabolic changes during this process and that it is driven by localized accumulation of bile acids.
机译:许多癌症在通过血管全身转移之前通过淋巴管转移区域。 然而,通过血液的转移比通过淋巴结更广泛地研究。 最近在科学,李等人。 (2019)通过表明黑色素瘤细胞在此过程中必须经历代谢变化,并且通过局部积聚的胆汁酸驱动,提供了新的淋巴结转移的新洞察力。

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